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Human Cell · 2023 · Vol. 36 · Issue 6 · Springer
The identification and development of therapeutic targets in cancer stem cells that lead to tumor development, recurrence, metastasis, and drug resistance is an important goal in cancer research. The hepatocellular carcinoma cell line Li-7 contains functionally different types of cells. Cells with tumor-forming activity are enriched in cancer stem cell-like CD13 + CD166 − cells and this cell population gradually decreases duri...