As the world's population grows, aquaculture is becoming a rapidly growing source of protein. Grass carp ( Ctenopharyngodon idella ) is one of the most important aquacultured species in China and has emerged as a significant commercial fish worldwide. However, grass carp reovirus (GCRV) poses a significant threat to grass carp aquaculture. This review covers GCRV biology, phylogeny, pathogenesis, immune response pathways, ther...

Global aquaculture production has been rising for several decades, with up to 76% of the total production from fish. However, the problem of fish diseases is becoming more and more prominent in today's context of pursuing sustainable aquaculture. Since the first fish genome assembly reported in 2002, genomic approaches have been successfully implemented in fish breeding to enhance disease resistance and reduce economic losses...

Fish harbour complex and dynamic microbiota in their mucosal surfaces. Due to the vital role of commensal microbiota in many biological functions including growth enhancement, nutrition, development, metabolism and immune response, many scholars have begun to refer to the microbiome as an ‘extended self’. Several studies have indicated that a normal microbiota contributes to fish health, and disturbances in microbial communiti...