Distal cholangiocarcinoma (dCCA) is a malignant tumor characterized by a challenging diagnosis, high invasiveness, and extremely poor prognosis. Research on dCCA is limited by the scarcity of reliable patient-derived preclinical tumor models. This study established a novel human distal cholangiocarcinoma cell line, CBC3T-3, and systematically characterized its biological properties, genomic features, and potential for clinical...

The increasing demand to harness offshore wind resources has pushed offshore wind turbines into deeper waters, making floating platforms more economically feasible than bottom-fixed ones. When the incident wind and wave forces act on the floating wind turbine, the floating platform will experience oscillations around its equilibrium position in six degrees of freedom (DOFs). Significant floater motions can affect the aerodynam...