A. Stark results 155
· Newest (Page 1/7, per page 25)
Author: A. Stark ×Clear All Filters
Search Results
Genomics workforce views on automating genomic reanalysis: trust, equity and governanceNARA Subscribed
Automation of genomic data reanalysis can increase diagnostic rates in a timely and cost-effective manner. However, implementing automated reanalysis brings with it both ethical and practical challenges. We sought to explore how clinical and laboratory staff view these challenges as part of a broader study piloting automated genomic reanalysis. Focus groups were conducted with 21 genetics health professionals recruited from a...
We investigated the effects of whole reservoir nitrogen (N) addition on kokanee growth in Dworshak Reservoir, Idaho. We hypothesized that N addition would improve the growth of kokanee ( Oncorhynchus nerka ) at a given level of abundance by increasing the availability of Daphnia , an important food source. Age‐specific size (length, weight, and relative weight) and biomass were compared for periods with and without N addition....
The Equilibrium ConundrumNARA Subscribed
The idea that natural systems tend to be at equilibrium dates back to the origin of the field of ecology and continues to underlie most ecological theory. However, empirical evidence for equilibrium dynamics in nature and in experiments is surprisingly elusive. Here, we address this conundrum by first exploring the history of equilibrium in ecological theory and the evidence for equilibrium dynamics in natural systems. We then...
A semi-mechanistic population pharmacokinetic-pharmacodynamic model to assess downstream drug-target effects on erythropoiesisNARA Subscribed
Erythropoiesis is a complex process that results in the production of erythrocytes from hematopoietic stem cells in the bone marrow. This work aimed to develop a population pharmacokinetic-pharmacodynamic (PKPD) model describing erythropoiesis and hemoglobin synthesis following bitopertin, an inhibitor of glycine transporter 1 (GlyT1), administration. Data from a Phase 1 clinical trial in 67 healthy subjects administered bitop...
Uncalibrated Single-Camera View Video Tracking of Head Impact Speeds Using Model-Based Image MatchingNARA Subscribed
Purpose This study evaluates the accuracy of a model-based image matching (MBIM) approach with model calibration for tracking head impact speeds in uncalibrated spaces from single-camera views. Methods Two validation datasets were used. The first included 36 videos of guided NOCSAE headform drops at varying camera positions (heights, distances, camera angles) where a speed gate measured vertical impact speed. The second datase...
‘Rainier Russet’ was released in 2020 as a medium- to late-maturing selection with russeted tubers. Total yields are less, but similar to controls ‘Ranger Russet’ and ‘Russet Burbank’, and U.S. No. 1 yields are higher than Russet Burbank with increased tubers > 284 g. Compared to controls, it has high protein levels, high specific gravity, excellent fry color and flavor ratings, low acrylamide potential, good post-harvest meri...