The submarine rudder configuration and arrangement significantly impact its hydrodynamic performance. This paper takes the SUBOFF standard submarine model as the research object, constructs a geometrically parameterized rudder fillet structure based on parabolic parametric equations, and adopts the improved delayed separation vortex (IDDES) turbulence model to carry out numerical simulation research on the submarine rounding f...

The infiltration of glioblastoma multiforme (GBM) is predominantly characterized by diffuse spread, contributing significantly to therapy resistance and recurrence of GBM. In this study, we reveal that microtubule deacetylation, mediated through the downregulation of fibronectin type III and SPRY domain-containing 1 (FSD1), plays a pivotal role in promoting GBM diffuse infiltration. FSD1 directly interacts with histone deacety...