Cytotoxic edema (CE) is a radiographic marker of early tissue injury in cerebral venous thrombosis (CVT) associated with poor outcomes, yet its mechanistic pathway remains unclear. We investigated whether intraparenchymal hemorrhage (IPH) mediates the association between CE and outcomes. We conducted a retrospective cohort study using the multicenter CLOT-VENUS registry, including acute CVT patients treated at two Comprehensiv...

Purpose Water scarcity is a growing concern, especially in regions with Mediterranean, arid, and semi-arid climates. Conventional indicators often use historical data, limiting accuracy under current hydrological changes. This study aims to develop an improved methodology for water scarcity assessment in Spain, enhancing the AWARE approach by integrating current reservoirs data and refined demand estimates to increase spatial...

Over the last decades, climate change biology has become a central field in global science, yet knowledge production and its inclusion in global strategies remain profoundly unequal. Our bibliometric analysis of over 580,000 records shows that ~80% of author affiliations come from Global North institutions, meaning that research agendas, theoretical frameworks, and priorities are still largely shaped outside the regions with t...

Chronic human immunodeficiency virus (HIV) infection continues to pose a major global health challenge, with an estimated 39.9 M cases and 1.3 M new infections per year. Up to 75%, of people with HIV (PWH) are currently being treated with antiretroviral therapy. The development of effective treatments for HIV requires a detailed understanding of the virus-host interaction. Often, mathematical models are used to inform this und...

The invasive spotted-wing drosophila, Drosophila suzukii , has emerged as a significant global pest over the past decade, threatening fruit production worldwide. The parasitoid Leptopilina japonica , presumed native to East Asia, has established adventive populations in Europe and North America and is increasingly recognized for its ability to parasitize substantial proportions of D. suzukii larvae across diverse habitats. Her...

H 2 is known as the main energy vector in the global energy transition. However, the use of fossil fuels for its production remains the most widely used primary source. Among the new alternatives for the organic production of H 2 , the Dark Fermentation process is an attractive technique since the raw material is residual biomass. H 2 is currently used for transport and fertilizer production. Hence, this study aims to evaluate...