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Longitudinal lipidomic markers of cardiac aging and risk of coronary heart disease in American Indians: the Strong Heart Family StudyNARA Subscribed
Age-related decline in left ventricular (LV) diastolic function is a hallmark of cardiac aging and an early precursor to cardiovascular disease. While dyslipidemia is a known driver of coronary heart disease (CHD), the molecular pathways linking lipid metabolism to cardiac aging and subsequent CHD risk remain poorly understood. Furthermore, longitudinal lipidomic profiling of cardiac aging in large human populations has not be...
Micropuncture and granular hydrogel scaffolds to surgically bioengineer a perfusable and stably patterned microvasculatureNARA Subscribed
Vascularization of implanted biomaterials is critical to reconstructive surgery and tissue engineering. Ultimately, the goal is to promote a rapidly perfusable hierarchical microvasculature that persists with time and can meet underlying tissue needs. We have previously shown that using a microsurgical technique, termed micropuncture (MP), in combination with porous granular hydrogel scaffolds (GHS) fabricated via interlinking...
First molecular phylogeny of mycoparasitic species of Sphaerellopsis isolated from rust fungi in AustraliaNARA Subscribed
Three species, Sphaerellopsis filum , S. macroconidialis , and S. paraphysata , from Queensland and Victoria, Australia, were identified and characterised by multilocus sequence analyses. This study clarifies earlier reports of Sphaerellopsis in Australia and provides the first report of S. filum in Australia. We also confirm the presence of S. macroconidialis and S. paraphysata in Australia. A single-locus phylogeny based on...
Background Benign paroxysmal positional vertigo (BPPV) is by far the most frequent cause of positional nystagmus (PN). However, PN may also be encountered in central lesions. In this case report we describe a patient with isolated positional vertigo and central PN which mimicked a lateral-canal cupulithiasis, including initial response to liberation maneuvers. Case Description A 44-year-old male patient reported new-onset posi...