This study aims to investigate the effect of milling on the natural radioactivity of Egyptian zircon sand, focusing on the gross alpha (α) and goss beta (β) activity concentrations, with additional evaluation of calcination and sulfuric acid leaching. Zircon samples were milled for different durations, and their gross α and gross β activity concentrations were measured using an ATOMTEX AT1329 sample counter. The measurements s...

The present research aimed to correlate changes in saline soil properties and cabbage agro-physiological attributes under compost-biochar co-application. The treatments used prior to cabbage cultivation were soil applications of compost/biochar mixtrure (CMB) at rates of 0 (CMB 0 ), 10 (CMB 10 ), and 20 (CMB 20 ) t ha –1 in a randomized complete block design with three replications. The CMB 20 was the effective practice for re...

Pimenta racemosa ( P. racemosa ) tree leaves are used in traditional medicine to alleviate flatulence and gastrointestinal disorders. Ulcerative colitis (UC) is a gastrointestinal inflammatory disease with well-known inflammatory and immunoregulatory pathological features. The complexity of the disease requires multi-targeted treatment. Because of their relative safety and effectiveness, natural products can be utilized as adj...

Intestinal ischemia reperfusion (II/R) is an abdominal critical case especially in neonates and during childhood affecting not only the intestinal tissue but also it could damage other remote organs including cardiac tissue even following surgical intervention. Immune homeostasis during II/R has a major role in controlling its progression. Thus, finding additive medical treatment besides the surgical one becomes an urgent need...

Piperazine-based compounds have garnered significant attention due to their notable biological and pharmacological activities, making them essential in fine chemical and pharmaceutical applications. In this study, we managed to synthesize a novel hybrid bis-cyanoacrylamide bearing the piperazine core via phenoxymethyl linker and incorporating sulphamethoxazole moiety. The novel compound was fully characterized using different...

Using a bioassay-guided fractionation approach, the most potent anti-psoriatic components of Aster squamatus herb, Aster chinensis stalks, and Aster chinensis flowers, cultivated in Egypt, were identified and evaluated against Imiquimod (IMQ)-induced psoriasis in female BALB/c mice and compared to standard drug, mometasone. The topical application of A. chinensis stalk methanolic extract exhibited the strongest anti-psoriatic...

New 3-substituted oxindole derivatives were designed and synthesized as antiproliferative agents. The antiproliferative activity of compounds 6a–j was evaluated against 60 NCI cell lines. Among these tested compounds, compounds 6f and 6g showed remarkable antiproliferative activity, specifically against leukemia and breast cancer cell lines. Compound 6f was the most promising antiproliferative agent against MCF-7 (human breast...