Biodiversity conservation is challenged not only by the lack of knowledge about species distributions but also by an often-overlooked factor: the unquantifiable uncertainty in the quality and reliability of the data used for decision-making. This challenge is intensified for migratory and overexploited species, such as the goliath catfish Brachyplatystoma filamentosum (‘piraíba’), where management decisions based on data of un...

Background Cardiovascular diseases are the leading cause of death worldwide. An important mechanism involved is the disruption in protein homeostasis by overactivation of the classical axis of the renin-angiotensin system. The counterregulatory axis counteracts these effects; however, the MrgD receptor has recently been described, and its effects are unknown. Thus, this study aims to evaluate the impact of MrgD deficiency on c...

Primates can share parasites with humans, and understanding host-parasite interactions is essential for evaluating the condition of wild primates, ecological dynamics, and One Health interface, which integrates humans, animal, and environmental health in shared environments. One example is filarial nematodes of the genus Mansonella , for which a lack of in-depth studies of symptoms or blood alterations limits our understanding...

Expanding integrative cytogenetic and molecular analyses is essential for understanding the evolutionary dynamics of chromosome number variation in fishes. This study presents the first cytogenetic characterization of Hypostomus sertanejo , an endemic species native to the semi-arid Jaguaribe River basin in Northeastern Brazil. Cytogenetic analysis revealed a diploid number of 2n = 52, which is the lowest documented for the ge...

Poisoning of companion animals resulting from exposure to analgesics intended for human use is a frequent and clinically relevant problem in veterinary practice, usually associated with administration without professional supervision. This can induce severe systemic toxicity. Diagnostic confirmation can be particularly challenging in cases presenting with nonspecific clinical signs or when conventional biological samples are u...

The aim of the present study was to evaluate the effects of dietary supplementation with the microalgae Nannochloropsis oculata and Phaeodactylum tricornutum , either separately or in combination, on growth performance, lipid profile, haematoimmunological parameters, and resistance to Edwardsiella tarda infection in Nile tilapia ( Oreochromis niloticus ). A total of 960 juvenile Nile tilapia (2.87 ± 0.68 g and 5.65 ± 0.16 cm)...

This study evaluated the effect of N-acetylcysteine ​​on oxidative biochemistry and bone damage during the development of ligature-induced experimental periodontitis in rats. The rats were divided into three groups (n = 8/group): control, experimental periodontitis (EP), or experimental periodontitis plus daily N-acetylcysteine administration (EP + NA) (100 mg/kg/day). Periodontitis was induced by bilateral silk ligatures on t...

Hematological studies in fish are sensitive indicators of physiological and pathological changes caused by aquatic pollution, including pharmaceutical contaminants. Among these pollutants, metformin is one of the most prevalent and has been associated with adverse effects on aquatic organisms. However, its impact on fish erythrocyte morphology remains poorly understood. This study evaluated the cyto- and genotoxic effects of m...

Abandoned mines are among the main sources of long-term soil contamination, often leaving behind persistent concentrations of potentially toxic elements (PTE) that pose environmental and health risks. Ribeiro da Serra Sb–Au mine, in Portugal, active from 1858 to 1890, has left a significant environmental legacy. This study mapped the spatial distribution of mine processing residues, elemental characterisation distinguishing be...

In its early years, the UN Decade on Ecosystem Restoration has mobilized unprecedented global commitments. Yet, measuring restoration success remains contested, particularly in megadiverse countries where the absence of standardized indicators and assessment protocols often leads to subjective decisions by environmental agencies. Here, we present a core set of leading indicators developed through a pioneering Brazil-led scienc...

Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...