Anne Pinto results 41
· Newest (Page 1/2, per page 25)
Author: Anne Pinto ×Clear All Filters
Search Results
Statistical analysis of in vitro assay data is a critical step towards a good interpretation of biological responses. However, it is still frequently undermined due to inappropriate statistical procedures, misinterpretation, insufficient statistical power—often resulting from small sample sizes—or poorly defined methodologies, in case of standardized tests. In line with practices commonly adopted in clinical studies and more r...
A metabolomic clock of population ageing: cross-cohort validation and associations with frailty and cognitive functionNARA Subscribed
Understanding the links between metabolism, ageing, and age-related phenotypes may clarify the role of ageing in disease onset and improve risk prediction. We conducted a cross-cohort assessment of biological age using broad-spectrum LC–MS metabolomics of 3,686 plasma samples in 2,295 participants, aged 20–89, from the UK Airwave study ( N = 960) and the Irish Longitudinal Study of Ageing ( N = 1,335). The nucleoside N 2 ,N 2...
Tree Regeneration After Unprecedented Forest Disturbances in Central Europe Is Robust but Maladapted to Future Climate ChangeNARA Subscribed
Central Europe has been a hotspot of forest disturbance during 2018–2020, with large pulses of tree mortality from drought and bark beetles. Post‐disturbance recovery is crucial for forest resilience and the continued provision of ecosystem services. We surveyed 849 plots in disturbance hotspots across 10 Central European countries to assess the state of early (3–5 years) post‐disturbance tree regeneration. Our specific object...
Wind dispersed tree species have greater maximum heightNARA Subscribed
Aim We test the hypothesis that wind dispersal is more common among emergent tree species given that being tall increases the likelihood of effective seed dispersal. Location Americas, Africa and the Asia‐Pacific. Time period 1970–2020. Major taxa studied Gymnosperms and Angiosperms. Methods We used a dataset consisting of tree inventories from 2821 plots across three biogeographic regions (Americas, Africa and Asia‐Pacific),...
Main conclusion Micro-analytical techniques to untangle Se distribution and chemical speciation in plants coupled with molecular biology analysis enable the deciphering of metabolic pathways responsible for Se tolerance and accumulation. Abstract Selenium (Se) is not essential for plants and is toxic at high concentrations. However, Se hyperaccumulator plants have evolved strategies to both tolerate and accumulate > 1000 µg Se...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
How much leaf area do insects eat? A data set of insect herbivory sampled globally with a standardized protocolNARA Subscribed
Herbivory is ubiquitous. Despite being a potential driver of plant distribution and performance, herbivory remains largely undocumented. Some early attempts have been made to review, globally, how much leaf area is removed through insect feeding. Kozlov et al., in one of the most comprehensive reviews regarding global patterns of herbivory, have compiled published studies regarding foliar removal and sampled data on global her...
Mammalian carnivores are considered a key group in maintaining ecological health and can indicate potential ecological integrity in landscapes where they occur. Carnivores also hold high conservation value and their habitat requirements can guide management and conservation plans. The order Carnivora has 84 species from 8 families in the Neotropical region: Canidae; Felidae; Mephitidae; Mustelidae; Otariidae; Phocidae; Procyon...