Supervised machine learning has become increasingly adopted in urban contamination studies, offering higher accuracy than conventional methods in interpreting complex datasets, distinguishing contamination zones, identifying key drivers, and defining geochemical fingerprints. Accordingly, this study explores the applicability and performance of Partial Least Squares Discriminant Analysis (PLS-DA) for classifying heavy metal co...

Non-communicable diseases, such as diabetes, cancer, as well as cardiovascular, metabolic, and central nervous system disorders stand for significant global health burden. Statins, as HMG-CoA reductase inhibitors, have emerged as a basis in the management of hypercholesterolemia and the prevention of cardiovascular disorders. In this review, we summarize the role of statins in a variety of pathologies, ranging from their well-...

The role of estrogen receptor (ER) and its related effects is crucial for growth of breast cancer cells. This study aimed to assess the cytotoxic impact of alizarin in models of breast cancer in vivo and investigate its antiestrogenic and apoptotic properties. MTT assay was used to evaluate alizarin cytotoxic effect against MCF7 and MDA-MB-231. In vivo, 30 mice were insulted with Ehrlich tumor cells. They were randomly allocat...

Schizophrenia (SCZ) is a complex, comprehensible mental condition that creates alienation from reality. SCZ is a mental disease, which is marked by progressive deficits in working memory, attention, and executive functioning. Because the disease’s etiology is unknown, current psychotherapy and pharmacological treatments merely treat symptoms and do not provide a cure. SCZ symptoms include hallucinations, delusions, disorganize...

This study aimed to investigate the effects of dietary selenium supplementation during the pre- and post-partum periods on milk production, blood parameters, reproductive performance in she-camels, and the growth of their offspring. Twenty pregnant Maghrabi she-camels, in their last three months of gestation, were randomly divided into four experimental groups and supplemented with selenium-methionine at levels of 0, 0.2, 0.3,...

Paving recycling technique gaining high attention for environmental and economic considerations. Bio oils among which Waste Engine Oil (WEO) can been used as aged asphalt rejuvenators. WEO has a bad effect on high temperature rutting performance in spite of it is a good flow improver at low temperature. In this research, Starch (ST) and Bone Glue (BG) as natural modifiers were used to increase the high temperature performance...

Introduction Metformin may provide a therapeutic benefit in different types of malignancy. Purpose We aimed at evaluating the effect of metformin as an adjuvant therapy to letrozole on estradiol and other biomarkers involved in the pathogenesis of breast cancer in overweight and obese postmenopausal women. Methods Seventy-five postmenopausal stages II–III breast cancer female patients were assessed for eligibility in an open-l...