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Neutrophil-related gene expression profile is associated with future paediatric bronchiectasis exacerbationsNARA Subscribed
Acute respiratory exacerbations in bronchiectasis are important as they impair quality of life and are associated with accelerated lung function decline. Yet, no validated methods exist to identify children at increased risk of exacerbations. We therefore determined if peripheral blood gene expression (GE) signatures can identify those at risk of an impending exacerbation. Thirty-one children with bronchiectasis had RNA extrac...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
San Francisco Bay, California, typically has chlorophyll a (chl- a ) concentrations below 10 µg L −1 , despite nutrient loadings exceeding those in many estuaries with recurring harmful algal blooms (HABs). However, in August 2022 there was a Heterosigma akashiwo (raphidophyte) bloom with chl- a concentrations exceeding 450 µg L −1 , resulting in widespread hypoxia and fish die-off. We used protist community (18S ribosomal rib...
P-glycoprotein (P-gp) is an ATP-dependent efflux transporter that contributes to cellular defense by exporting xenobiotics. While well characterized in mammals, its inducibility and physiological regulation in fish remain poorly understood. This study examined the functional induction of P-gp in juvenile rainbow trout (Oncorhynchus mykiss) hepatocytes following xenobiotic exposure and assessed how energy status (fed vs. fasted...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Novel Method for Collecting Skin Microbiome Samples From Free‐Ranging Bottlenose DolphinNARA Subscribed
Cetacean skin microbiome samples are traditionally collected by swabbing the skin of captured animals or using skin tissue from remote biopsies. The effects of different sampling methods are not well understood, and factors such as swab type and storage methods may affect the microbiome. The objective of this study was to determine if samples collected by swabbing biopsied skin from bottlenose dolphins yield sufficient microbi...