Lynch syndrome predisposes to multiple cancer types, including urological malignancies. However, no evidence-based recommendations for surveillance of urological malignancies currently exist. In this systematic review, we aim to describe the current evidence regarding surveillance for these cancers. A systematic literature search was conducted using MEDLINE, searching for urological malignancies, Lynch syndrome, and surveillan...

Pollinator conservation schemes typically focus on conserving existing, restoring degraded, or creating new wild bee habitats. Their effectiveness depends on dispersal corridors enabling habitat colonization by bees. However, the role of seminatural linear landscape structures (LLS) in connecting pollinator communities across intensively managed landscapes remains poorly understood. We analyzed 953 occurrences of wild bees com...

Several legal acts mandate that management agencies regularly assess biological populations. For species with distinct markings, these assessments can be conducted noninvasively via capture‐recapture and photographic identification (photo‐ID), which involves processing considerable quantities of photographic data. To ease this burden, agencies increasingly rely on automated identification (ID) algorithms. Identification algori...

Traumatic brain injury (TBI) remains a major global health challenge with a need for improved diagnostic and prognostic biomarkers. This study aimed to evaluate the biomarker potential of extracellular vesicle (EV)-encapsulated glial fibrillary acidic protein (EV-GFAP), neurofilament light chain (EV-NfL), total tau (EV-T-Tau), and ubiquitin carboxy-terminal hydrolase L1 (EV-UCH-L1) in TBI. A cohort of 93 trauma patients (75 wi...

Riparian floodplains are important regions for biogeochemical cycling, including nitrogen. Here, we present MAGs from nitrifying microorganisms, including ammonia‐oxidising archaea (AOA) and comammox bacteria from Slate River (SR) floodplain sediments (Crested Butte, CO, US). Additionally, we explore MAGs from potential nitrite‐oxidising bacteria (NOB) from the Nitrospirales . AOA diversity in SR is lower than observed in othe...

Sarcopenia increases the risk of frailty, morbidity, and mortality in older adults. Resistance exercise training improves muscle size and function; however, the response to exercise training is variable in older adults. The objective of our study was to determine both the age-independent and age-dependent changes to the transcriptome following progressive resistance exercise training. Skeletal muscle biopsies were obtained bef...

Aim To determine which riverine invertebrate traits respond consistently to anthropogenic impacts across multiple biogeographic regions. Location Europe. Time Period 1981–2021. Major Taxa Studied Riverine invertebrates. Methods We compiled a database of riverine invertebrate community time series for 673 sites across six European countries spanning six freshwater ecoregions. We compared trait responses to anthropogenic impacts...

The aim of this study is twofold: i) to determine innovative yet sensitive endpoints for sulfoxaflor and ii) to develop best practices for innovative teaching in ecotoxicology. To this end, a group of 52 MSc students participated in an environmental hackathon , during which they did creative toxicity testing on 5 freshwater invertebrate species: Daphnia magna, Chironomus riparius, Asellus aquaticus, Lymnaea stagnalis, and Anis...

As alien invasive species are a key driver of biodiversity loss, understanding patterns of rapidly changing global species compositions depends upon knowledge of invasive species population dynamics and trends at large scales. Within this context, the Ponto-Caspian region is among the most notable donor regions for aquatic invasive species in Europe. Using macroinvertebrate time series collected over 52 years (1968–2020) at 26...

This paper describes the distribution, abundance and seasonal variation in blue whales (BWs) on the south coast of Sri Lanka, off Mirissa, where they are faced with anthropogenic threats. Data collection encompassed opportunistic sightings by whale-watching (WW) operations. This study revealed that large aggregations of BWs consistently overlapped with busy shipping lanes located between Dondra Head and Galle within important...

Aging slowly erodes skeletal muscle strength and mass, eventually leading to profound functional deficits and muscle atrophy. The molecular mechanisms of skeletal muscle aging are not well understood. To better understand mechanisms of muscle aging, we investigated the potential role of ATF4, a transcription regulatory protein that can rapidly promote skeletal muscle atrophy in young animals deprived of adequate nutrition or a...