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Genetic ancestry proportion influences risk of adverse events from tuberculosis treatment in BrazilNARA Subscribed
Tuberculosis (TB) treatment is highly effective, but response to therapy varies by geography and population subgroups. We assessed differences in TB treatment response in a representative and heterogeneous Brazilian population. We estimated genetic ancestry according to major genetic ancestry groups (African, European, and Amerindian) in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort usi...
Decade-scale recovery of the Eyjafjallajökull ice cap, Iceland, after the 2010 summit eruptionNARA Subscribed
Several eruptions at glaciated volcanoes have been witnessed during the last two centuries. However, most studies have focused on understanding the volcanic products or the hazard implications. Less attention has been put into analyzing the long-term effects on the glaciers. The 2010 summit eruption of Eyjafjallajökull (Iceland) provides an excellent opportunity to study such impacts by investigating how individual areas of th...
The hyperiid amphipod Brachyscelus rapacoides is a warm-water species associated with gelatinous zooplankton. In the Mediterranean it has been reported in association with Rhopilema nomadica in both Israel and Turkey. Here, we document the first record of B. rapacoides in Greek waters, representing the first confirmed record for Europe, based on both morphological examination and DNA barcoding of the mitochondrial COI gene. Sp...
Evaluation of siRNA-mediated knockdown of heat shock protein 16.2 in adult Acropora cervicornisOA Marine
Acropora cervicornis is a critically endangered Caribbean coral species facing a precipitous decline due to disease and thermal bleaching. To combat the loss of ecologically important reef-building corals, novel molecular approaches can be used to understand mechanisms of resilience and ultimately provide a means to modulate coral performance. In this study, we tested a recently developed method for gene knockdown in adult cor...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Addressing urgent conservation issues, such as the drastic declines of North American migratory birds, requires creative, evidence‐based, efficient, and collaborative approaches. The abundance of over 50% of monitored North American shorebird populations has declined by over 50% since 1980. To address these declines, we developed a partnership of scientists and practitioners called the Shorebird Science and Conservation Collec...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
The interdisciplinary study of volcanic processes, which extend across all timescales and lengths, requires a multitude of approaches, ranging from analogue and numerical modelling to observations and fieldwork and extending to mathematics. A conference was held at the East African Institute for Fundamental Research, affiliated with the University of Rwanda, a country which, along with the Democratic Republic of Congo, present...
Short-term effects of Greenlandic glacial rock flour on soil physical properties and maize yieldNARA Subscribed
Greenlandic glacial rock flour (GRF) serves as a valuable source of silicate minerals for CO₂ uptake through enhanced weathering. Additionally, its physico-chemical properties may influence soil hydro-physical characteristics and may also have a separate effect on crop yields. This study evaluated the effects of GRF application at 50 and 100 t/ha, along with an unamended control, on soil water content at field capacity (FC), p...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Can Solar‐Powered Irrigation Systems Naturally Meet Crop Water Requirements? Proof of Concept From a Case Study in Sub‐Saharan AfricaNARA Subscribed
Irrigation scheduling is crucial for ensuring precise water delivery to crops. However, in many sub‐Saharan African irrigation schemes, water is applied without considering crop water needs, resulting in low crop water productivity and low yields. Solar‐powered irrigation systems can automatically meet these needs by utilizing solar radiation, which drives both evapotranspiration and solar panel power production for pumping. T...