C. Botella results 11
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Evaluation of computational tools for the prediction of CRISPR/SpCas9 gRNA activity in plantsNARA Subscribed
CRISPR/Cas9 technologies are now routinely used in plant research, with guide RNA (gRNA) design being a critical determinant of genome editing success. However, rational design of highly active gRNAs is challenging due to complex sequence and biochemical factors affecting activity. While numerous computational prediction tools have been developed, they are predominantly trained on animal cell or microbial data and their perfor...
Understanding how and why plants are driven to extinction is important if future extinctions are to be prevented. Here we examined reasons for extinctions of plants using data from the South African Red List, which includes 33 Extinct taxa from 15 families and 24 genera including seven infraspecific taxa. We also compared Extinct taxa with those that are threatened and not-threatened, exploring predictors of extinction based o...
Functional traits driving species role in the structure of terrestrial vertebrate scavenger networksNARA Subscribed
Species assemblages often have a non‐random nested organization, which in vertebrate scavenger (carrion‐consuming) assemblages is thought to be driven by facilitation in competitive environments. However, not all scavenger species play the same role in maintaining assemblage structure, as some species are obligate scavengers (i.e., vultures) and others are facultative, scavenging opportunistically. We used a database with 177...
Scavenging in the Anthropocene: Human impact drives vertebrate scavenger species richness at a global scaleNARA Subscribed
Understanding the distribution of biodiversity across the Earth is one of the most challenging questions in biology. Much research has been directed at explaining the species latitudinal pattern showing that communities are richer in tropical areas; however, despite decades of research, a general consensus has not yet emerged. In addition, global biodiversity patterns are being rapidly altered by human activities. Here, we aim...
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