There is growing evidence that morphological change is a widespread response to the warming climate. The empirical basis for understanding this process has, to date, largely been correlative analyses of morphological time series. However, it is not clear what constitutes sufficient temporal sampling for assessing long-term morphological change. We analyzed two long-term high-quality morphological datasets, one including 33 spe...

Necrotizing enterocolitis (NEC) is the most common surgical emergency in preterm infants; nonetheless, besides supportive measures, no treatment is available. NEC significantly increases length of hospitalization of preterm infants, causes severe morbidity and up to 70% mortality. Despite limited understanding of the underlying mechanisms, prematurity, dysbiosis and an underdeveloped immune system are known to increase the ris...

The Siberian Arctic Ocean (SAO) is the largest integrator and redistributor of Siberian freshwater resources and acts to significantly influence the Arctic climate system. Moreover, the SAO is experiencing some of the most notable climate changes in the Arctic, and advection of anomalous Atlantic- (atlantification) and Pacific-origin (pacification) inflow waters and biota continue to play a major role in reshaping the SAO in r...

Attention-deficit/hyperactivity disorder, or ADHD, is a neurodevelopmental disorder with poorly understood molecular mechanisms. Recent studies have proposed that gene expression involved in regulating synaptic transmission in the striatum may play a role in ADHD pathogenesis. To explore the molecular basis of ADHD, we utilized proteomic analysis using whole striatal tissues from early adult thyroid hormone-responsive protein-...

While many jurisdictions have phased out use of bisphenol A (BPA), there is increasing exposure to mixtures of BPA alternatives. Like BPA, some alternatives perturb nuclear hormone receptors and are endocrine disruptors. We used high-throughput transcriptomics (HTTr) to evaluate the potency and modes of action of seven mixtures of BPA alternatives and their 12 individual components in breast cancer cells. Our aim was to explor...

Forest allocation of net primary productivity (NPP) to reproduction (carbon required for flowers, fruits, and seeds) is poorly quantified globally, despite its critical role in forest regeneration and a well‐supported trade‐off with allocation to growth. Here, we present the first global synthesis of a biometric proxy for forest reproductive allocation (RA) across environmental and stand age gradients from a compiled dataset o...