This position paper was collaboratively written during the international expert symposium “EU Chemicals Assessment - Risk- or Hazard-based?” that was organised by the German Federal Institute for Risk Assessment (BfR) in Berlin on November 27th and 28th 2025. Twenty experts from several institutions and European countries considered the scientific merits of both hazard-based and risk-based approaches to chemical safety assessm...

The iconic sand dune systems of Minjerribah (North Stradbroke Island), in southeastern Queensland, Australia, host numerous lakes and swamps containing organic‐rich sediment deposits that record changes in climate, fire and surrounding vegetation. Palaeoenvironmental reconstructions from individual locations can provide insights into changes in the environment, but determining the regional extent of these changes is seldom pos...

Current approaches for the assessment of environmental and human health risks due to exposure to chemical substances have served their purpose reasonably well. Nevertheless, the systems in place for different uses of chemicals are faced with various challenges, ranging from a growing number of chemicals to changes in the types of chemicals and materials produced. This has triggered global awareness of the need for a paradigm s...

Chronic calorie restriction (CR) results in lengthened lifespan and reduced disease risk. Many previous studies have implemented 30–40% calorie restriction to investigate these benefits. The goal of our study was to investigate the effects of calorie restriction, beginning at 4 months of age, on metabolic and physical changes induced by aging. Male C57BL/6NCrl calorie restricted and ad libitum fed control mice were obtained fr...

Conservation of migratory birds requires knowledge of breeding and nonbreeding ranges and the connections between them. European turtle doves ( Streptopelia turtur ) are Palearctic-African long-distance migrants with wintering areas in the Sub-Saharan belt that are classed as vulnerable due to strong population declines. However, detailed non-breeding locations of individuals from different migratory flyways are unknown. To id...

Ironwood ( Casuarina equisetifolia subsp. equisetifolia ) trees on Guam have been in decline since 2002. This study applied proportional odds logistic multiple regression modeling to a set of biological variables in order to find significant decline predictors as a first step towards identifying pathogenic contributors. Based on the analysis of a set of 77 medium and large trees, the bacterium Ralstonia solanacearum and the fu...

Aim Plants occurring on high‐alpine summits are generally expected to persist due to adaptations to extreme selective forces caused by the harshest climates where angiosperm life is known to thrive. We assessed the relative effects of this strong environmental filter and of other historical and stochastic factors driving plant community structure in very high‐alpine conditions. Location European Alps, Écrins National Park, Fra...