This study evaluated the naturally occurring microorganisms within the gastrointestinal tract (GIT) and yolk sacs of day-old commercial broiler chicks. Across 6 independent trials, day-old chicks ( n = 10 per trial) were obtained from various commercial hatcheries, humanely euthanized, and necropsied. The entire intestine (duodenum to colon) and the yolk sac were isolated, homogenized, serially diluted, and plated onto selecti...

Globally, many plant communities are reorganizing in response to climate change, often at different rates than associated fauna. Asynchrony in range expansion between plants and fauna could alter biotic constraints on plant populations. Tropical mangroves are limited by folivory, but little is known about the importance of herbivory on mangroves near distributional range limits in subtropical regions. We hypothesized that herb...

Three new isatin–pyridine-2-oxime hybrids (AM01–03) were synthesized and experimentally evaluated as reactivators of acetylcholinesterase (AChE) inhibited by a surrogate of the nerve agent A-242, in comparison with their 4-oxime isomers previously reported by our research group. Furthermore, the interactions of these molecules within the AChE/A-242 complex were assessed through docking and molecular dynamics (MD) simulations....

Climate change poses an unprecedented risk to fisheries ecosystems and economies globally. Ocean warming has led to observed geographic shifts and changes in the productivity of fish stocks. Due to the rapid pace of change in many of the world's oceans, there is a critical need to develop and apply scientific knowledge and tools that can help account for non‐stationarity and integrate climate and ecosystem drivers into fishery...

The computational cost of dynamical downscaling limits ensemble sizes in regional downscaling efforts. We present a generative-AI approach to greatly expand the scope of such downscaling, enabling fine-scale future changes to be characterised including rare extremes that cannot be addressed by traditional approaches. We test this approach for New Zealand, where heterogenous regional climate effects are anticipated. End-of-cent...

Rationale Mu opioid receptor (MOR) analgesics like morphine have high intrinsic MOR efficacy but produce side effects. Lower efficacy MOR agonists like buprenorphine can produce analgesia with improved safety. We recently described a series of novel phenylmorphan-based MOR agonists with graded MOR efficacies, including several with sub-buprenorphine efficacies, and we described their acute effectiveness in mice to produce (a)...

Disturbance effects are rarely distributed uniformly over space or time. Thus, scaling up the effects of disturbances requires detailed measurements across multiple spatial scales. To characterize disturbance from wrack we used monthly images from an unmanned aerial vehicle (UAV) in a 144,500 m 2 Spartina alterniflora saltmarsh on Sapelo Island, Georgia (USA), from March 2020 to December 2022. Prior work as well as the results...