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Inflammatory Factor IL1α Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca2+/CaMK2b PathwayNARA Subscribed
Spinal cord injury (SCI) is one of the most devastating traumas, and the aberrant proliferation of astrocytes usually causes neurological deficits. However, the mechanism underlying astrocyte over-proliferation after SCI is unclear. Grin2c (glutamate ionotropic receptor type 2c) plays an essential role in cell proliferation. Our bioinformatic analysis indicated that Grin2c and Ca 2+ transport functions were inhibited in astroc...
Marine heatwaves (MHWs) are a type of widespread, persistent, and extreme marine warming event that can cause serious harm to the global marine ecology and economy. This study provides a systematic analysis of the long-term trends of MHWs in the Eastern China Marginal Seas (ECMS) during summer spanning from 1982 to 2022, and occurrence mechanisms of extreme MHW events. The findings show that in the context of global warming, t...