Christian Neumann results 48
· Newest (Page 1/2, per page 25)
Author: Christian Neumann ×Clear All Filters
Search Results
EEG-based assessment of sustained attention in geriatric inpatients: a feasibility studyNARA Subscribed
Sustained attention is a core cognitive function, frequently declines with age and neurological disease, and is highly relevant for functional outcomes in geriatric populations. Electroencephalography (EEG) offers high temporal resolution for assessing attentional processes, but its feasibility in multimorbid geriatric inpatients remains insufficiently characterized. This study evaluated the procedural and methodological feasi...
A new genus and species of Galeritidae (Echinoidea, Echinoneoida) from the Upper Campanian (Cretaceous) of N GermanyNARA Subscribed
A new genus and species of Cretaceous echinoneoid echinoid, Catinogalerus alexanderi gen. et sp. nov., is described and illustrated on the basis of 27 specimens originating from the Late Campanian of Kronsmoor and Rügen (both northern Germany). Morphologically, the new taxon appears closest to Galerites which it resembles in many aspects. The concave, saucer-shaped apical region, and cone-shaped protrusions of the genital plat...
Terrigenous inputs link nutrient dynamics to microbial communities in a tropical lagoonNARA Subscribed
Nutrient availability drives community structure and ecosystem processes, especially in tropical lagoons that are typically oligotrophic but often receive allochthonous inputs from land. Terrestrially derived nutrients are introduced to tropical lagoons by surface runoff and submarine groundwater discharge, which are influenced by seasonal precipitation. However, terrigenous inputs presumably diminish along the onshore–offshor...
Driving a Circular Economy: Nudging and Innovative Strategies for Promoting Post-Consumer Recycled Plastic Home-AppliancesNARA Subscribed
The various social and ecological crises of our time are leading to ever louder calls for a sustainable transition towards a sustainable circular economy. As a result, the recycling of plastics is increasingly being brought to the foreground and the increased use of post-consumer recyclate (PCR) is being called for. However, the acceptance of products made from PCR plastic and how this can be increased is still largely unclear...
Avenues towards reconciling wild and managed bee proponentsNARA Subscribed
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
TGFβ signalling pathway impacts brain metastases profiles in locally advanced colorectal cancerNARA Subscribed
Rationale Colorectal Cancer (CRC) represents the third most common type of cancer in Germany and the second most common cancer-related cause of death worldwide. Distant metastases are still the main limit for patient survival. While liver metastases as well as peritoneal carcinomatosis can often either be resected or treated with systemic therapy, little options remain for brain metastases. Additionally, a number of studies ha...
The Toxicology Investigators Consortium 2022 Annual ReportNARA Subscribed
Canonical circuit computations for computer visionNARA Subscribed
Advanced computer vision mechanisms have been inspired by neuroscientific findings. However, with the focus on improving benchmark achievements, technical solutions have been shaped by application and engineering constraints. This includes the training of neural networks which led to the development of feature detectors optimally suited to the application domain. However, the limitations of such approaches motivate the need to...
Heart failure is a syndrome that can result from impaired heart muscle contractions like in dilative cardiomyopathy but also from hypertrophic obstructive cardiomyopathy (HOCOM). A pharmacological therapy might lie in Ca 2+ -sensitizing or Ca 2+ -desensitizing drugs, respectively. Such drugs are thought to be omecamtiv mecarbil (OME) and mavacamten (MYK-461), respectively. Their function in contracting human muscle is not full...
The use of recreational drugs like ephedrine, norephedrine, 3,4-methylenedioxymethamphetamine (MDMA), and mescaline can lead to intoxication and, at worst, to death. One reason for a fatal course of intoxication with these drugs might lie in cardiac arrhythmias. To the best of our knowledge, their inotropic effects have not yet been studied in isolated human cardiac preparations. Therefore, we measured inotropic effects of the...
Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H2-histamine-receptor activation in isolated atria of transgenic miceNARA Subscribed
Histamine exerts cAMP-dependent positive inotropic effects (PIE) and positive chronotropic effects (PCE) on isolated left and right atria, respectively, of transgenic mice which overexpress the human H 2 -receptor in the heart (=H 2 -TG). To determine whether these effects are antagonized by phosphodiesterases (PDEs), contractile studies were done in isolated left and right atrial preparations of H 2 -TG. The contractile effec...
The contribution of sediments to nutrient cycling of the coastal North Sea is strongly controlled by the intensity of fluxes across the sediment water interface. Pore‐water advection is one major exchange mechanism that is well described by models, as it is determined by physical parameters. In contrast, biotransport (i.e., bioirrigation, bioturbation) as the other major transport mechanism is much more complex. Observational...
Dead urchin walking: resilience of an arctic Strongylocentrotus to severe skeletal damageNARA Subscribed
The ability of bottom-dwelling marine fauna to repair injured body parts is critical to the survival of individuals from disturbances that inflict wounds. The phylum Echinodermata, in particular, exposes a pronounced ability to regenerate skeletal damages. Regeneration of lost body parts of stellate echinoderms (crinoids, asteroids and ophiuroids) is a well-documented phenomenon, whereas sea urchins (echinoids) have received m...