Christopher Taylor results 243
· Newest (Page 1/10, per page 25)
Author: Christopher Taylor ×Clear All Filters
Search Results
Regulation of PDGF-BB signaling in placental pericytes by soluble PDGFRβ isoforms: implications for fetoplacental vascular developmentNARA Subscribed
Vascular remodeling within the developing fetus and placenta is essential for supporting the growth and function of emerging tissues and organs. Pericytes (PCs) play a central role in stabilizing and maturing microvascular networks by extending along endothelial cells (ECs) and reinforcing vessel integrity. In the placenta, as in other organs, PC–EC communication is mediated in part by platelet-derived growth factor-BB (PDGF‑B...
Congressionally designated wilderness offers the highest level of land protection in the USA, comparable to category 1b wilderness as defined by the International Union for Conservation of Nature, yet wilderness areas face impacts of climate change. Researchers and managers increasingly recognize the immense challenge of stewarding wilderness in a changing climate. Although responding to climate change is considered a wicked p...
Characterising the mycobiome of healthy and wounded reef sharks in the Seychelles archipelagoNARA Subscribed
Sharks frequently sustain cutaneous injuries throughout their lifetimes, yet subsequent infections are surprisingly rare, and wounds appear to heal rapidly. This has led scientists to explore the potential mechanisms behind shark skin’s putative ‘superior’ capacity for fending off infection. Interestingly, research has turned to the skin-associated microbiome for the answer. Although exploration of the bacterial microbiome has...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Distributed optical fibre sensing (DOFS) is a technology that enables continuous, real-time measurements of a range of environmental parameters along the length of a fibre optic cable. In this article, we review the recently emerged applications of DOFS techniques in physical oceanography and offer a perspective on the technology's potential for future growth within the field. The introduction of DOFS to physical oceanography...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Addressing urgent conservation issues, such as the drastic declines of North American migratory birds, requires creative, evidence‐based, efficient, and collaborative approaches. The abundance of over 50% of monitored North American shorebird populations has declined by over 50% since 1980. To address these declines, we developed a partnership of scientists and practitioners called the Shorebird Science and Conservation Collec...
Comparative evaluation of pressure plate and evaporation–dewpoint methods for improved irrigation decision-makingNARA Subscribed
Accurate determination of soil water retention parameters is essential for optimizing irrigation decisions, but inconsistencies between laboratory methods can lead to different recommendations. This study aims to evaluate and compare the Pressure Plate (PP) method and the Evaporation–Dewpoint method (Hyprop™ and WP4C™, referred to as HW) to see how they affect irrigation threshold estimates in different soil types. A total of...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Background As the number of BME clinical immersion experiences expands across university curricula, there is a growing opportunity for BME educators to share practical insights gained from implementing clinical immersion courses. Despite the growing scholarship exploring BME clinical immersions, a significant need for robust exploration remains as we work to understand the impact of such programs on student learning. Purpose T...
Implementation of a Healthcare Implicit Bias Training across Three Oncology Care SettingsNARA Subscribed
The purpose of this study was to describe evaluation outcomes, including reach, satisfaction with training, and strategies to increase uptake of implicit bias training across three cancer centers in Washington, DC. From October 25, 2022, to March 29, 2023, oncology clinicians and staff were asked to complete an implicit bias training and post-training survey. Strategies used to increase training reach included identifying and...