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Contrasting the genetic architecture of cardiac glutathione against other organs: unveiling a unique tissue-specific locusNARA Subscribed
Glutathione is a ubiquitous antioxidant with critical roles in xenobiotic clearance and aerobic metabolism. Reduced glutathione (GSH) is converted to its oxidized counterpart, GSSG, in the process of neutralizing free radicals and maintaining biochemical homeostasis. An imbalance between free radical generation and antioxidant protection leads to oxidative stress and diminished GSH concentrations. Polymorphisms in GSH synthesi...
Enumeration of organisms occurring in the intestinal tract and yolk sac of day-old chicks from commercial hatcheriesNARA Subscribed
This study evaluated the naturally occurring microorganisms within the gastrointestinal tract (GIT) and yolk sacs of day-old commercial broiler chicks. Across 6 independent trials, day-old chicks ( n = 10 per trial) were obtained from various commercial hatcheries, humanely euthanized, and necropsied. The entire intestine (duodenum to colon) and the yolk sac were isolated, homogenized, serially diluted, and plated onto selecti...
We provide best practices for estimating the dissipation rate of turbulent kinetic energy, ε, from velocity measurements in an oceanographic context. These recommendations were developed as part of the Scientific Committee on Oceanographic Research (SCOR) Working Group #160 “Analyzing ocean turbulence observations to quantify mixing”. The recommendations here focus on velocity measurements that enable fitting the inertial subr...
Two Contrasting Demographic Processes Shape the Divergence and Evolution of the Widespread Arid Zone Specialist, Petrogale lateralisNARA Subscribed
Organisms living in arid environments are predicted to be at increased risk of extinction under climatic and anthropogenic change. Response to past climate change can provide some insights into these risks; however, our understanding of the diversification and evolutionary history of many arid‐adapted species is still limited, particularly in Australia. Here, we evaluate the demographic and evolutionary history of a widespread...
The impact of high rainfall events on the submesoscale salinity field in a coastal sea: Greater Cook Strait, New ZealandNARA Subscribed
River inflow into the coastal oceanic environment can result in low salinity submesoscale features (LSMFs). The enhanced water column stability sustained within these coherent structures affects local biological productivity. With‐event and seasonal variability of LSMFs were investigated in a coastal sea — Greater Cook Strait — that is characterised by strong tidal and wind forcing as well as being forced at the land‐sea bound...
Aotearoa New Zealand’s marine carbon cycle in a changing climate – Current understanding and future directionsNARA Subscribed
The marine system plays a critical role in the global climate cycle, as a major control of atmospheric carbon dioxide (CO 2 ). Marine primary production (photosynthesis) and remineralisation of organic carbon (respiration, degradation) determine the amount of CO 2 sequestered in marine sediments and deep‐water environments on century to millennial timescales. The stocks and fluxes of the marine carbon cycle are susceptible to...
The rapid structural evolution and extensive metabolism of synthetic cannabinoid receptor agonists (SCRAs) following consumption makes their detection in biological samples challenging, especially in urine. In vitro metabolite identification studies are an essential tool for identifying analytical targets to confirm SCRA consumption in clinical and forensic toxicology casework. Systematic studies on structurally related SCRAs...
Purpose This study aimed to examine the effects of a single dose of a betalain-rich concentrate (BRC) on determinants of running performance and recovery lactate clearance. Methods In this a randomized, triple-blind, placebo-controlled, crossover trial, 17 male recreational runners (Age: 19.0 ± 1.0 years; Height: 176.8 ± 6.2 cm; Weight: 70.62 ± 8.1 kg; Body fat: 12.8 ± 0.03%; VO 2max : 58.9 ± 8.6 ml/kg/min) consumed an acute d...
Cross‐Continental Analysis Shows That Disturbance Effects on Reptile Body Condition Do Not Predict Abundance ResponsesNARA Subscribed
Ecological disturbances are discrete events that alter or transform the physical, chemical, or biological characteristics of ecosystems. Disturbance can cause animal populations to decline and, according to the risk‐disturbance hypothesis and population collapse framework, these declines can be predicted by declines in animal body condition. However, no research has empirically examined the general relationship between body co...
Turbulent mixing properties were directly observed to understand the interactions and overlapping events of wind-forced and tidally forced boundary layers in a deep, weakly stratified coastal sea. Te-Moana-o-Raukawa / Cook Strait of Aotearoa / New Zealand is an 𝒪(200 m) deep, energetic strait, known to experience both strong tidal currents and high wind speeds. More than 𝒪(40 000) quality-controlled turbulence observations wer...
Aim The urgency for remote, reliable and scalable biodiversity monitoring amidst mounting human pressures on ecosystems has sparked worldwide interest in Passive Acoustic Monitoring (PAM), which can track life underwater and on land. However, we lack a unified methodology to report this sampling effort and a comprehensive overview of PAM coverage to gauge its potential as a global research and monitoring tool. To address this...
Characterisation of autophagy induction by the thiopurine drugs azathioprine, mercaptopurine and thioguanine in THP-1 macrophagesNARA Subscribed
Activating autophagy may be therapeutically beneficial, and we have previously shown that azathioprine (AZA), an immunomodulatory drug, induces autophagy. Here, we evaluated the induction of autophagy by the thiopurines AZA, mercaptopurine (6-MP) and thioguanine (6-TG) in THP-1 macrophages and investigated the mechanism of action in the context of this cellular process. The cytotoxicity of thiopurines was evaluated using an LD...
Characterizing Juvenile Common Snook and Tarpon Habitat to Guide Conservation and Restoration of Coastal WetlandsNARA Subscribed
To conserve or restore juvenile fish habitat, resource managers, restoration practitioners, and engineers need fine-scale information to understand what conditions they need to preserve or what specifications are needed to create new habitat. The objective of this study was to develop statistical models using a dataset of 18 coastal ponds in Southwest Florida, USA, to predict the abundance of juvenile common snook Centropomus...