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Traditional and Band-Assisted Nordic Hamstring Training Improves Knee Flexor Strength and Hip Range of MotionNARA Subscribed
Purpose To compare the training effects of traditional (TRAD) and band‑assisted (NHE ASSIST ) Nordic Hamstring Exercise on knee flexor force‑length characteristics, NHE execution, and hip range of motion (ROM). Methods Forty-five male ( n = 24) and female ( n = 21) collegiate athletes were recruited from a variety of sports (soccer, basketball, Gaelic football, rugby, athletics, and netball) to partake in a twice-weekly 8-week...
Coincident changes in abundance and phenology pose a challenge for interpreting abundance indices derived from monitoring programs. In the San Francisco Estuary, long-term monitoring programs have documented changes in overall longfin smelt ( Spirinchus thaleichthys ) abundance as well as regional differences in presence over time. Seasonal patterns in regional presence of longfin smelt through its life cycle were developed us...
Germline copy number variants and endometrial cancer riskNARA Subscribed
Known risk loci for endometrial cancer explain approximately one third of familial endometrial cancer. However, the association of germline copy number variants (CNVs) with endometrial cancer risk remains relatively unknown. We conducted a genome-wide analysis of rare CNVs overlapping gene regions in 4115 endometrial cancer cases and 17,818 controls to identify functionally relevant variants associated with disease. We identif...
Purpose Dietary analysis is an important part of the sports nutrition practitioners’ role, however the ability to accurately collect and analyze dietary intake data is questionable. The remote food photography method (RFPM) has been proposed as a low-burden and potentially valid approach to collecting and interpreting dietary intake data. Preliminary research suggests that this is valid in some athletic populations, however th...
The acute and repeated bout effects of multi-joint eccentric exercise on physical function and balance in older adultsNARA Subscribed
Purpose Eccentric muscle actions generate high levels of force at a low metabolic cost, making them a suitable training modality to combat age-related neuromuscular decline. The temporary muscle soreness associated with high intensity eccentric contractions may explain their limited use in clinical exercise prescription, however any discomfort is often alleviated after the initial bout (repeated bout effect). Therefore, the ai...
Fissure eruptions initiate with magma ascending and spreading through cracks in the ground that can extend for kilometres at the surface. Eruptions eventually localise to form one or a few persistent conduits and ultimately an array of discrete cones or craters. We built a new experimental apparatus to investigate the influences of fissure shape and wall-rock temperature on localisation within a volcanic fissure, and the therm...
Rangelands in a fragmented grass-dominated landscape are vulnerable to tree invasion from roadsidesNARA Subscribed
Roadsides can be vectors for tree invasion within rangelands by bisecting landscapes and facilitating propagule spread to interior habitat. Current invasive tree management in North America’s Great Plains focuses on reducing on-site (i.e., interior habitat) vulnerability through on-site prevention and eradication, but invasive tree management of surrounding areas known to serve as invasion vectors, such as roadsides and public...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Stage of colorectal cancer diagnosis for immigrants: a population-based retrospective cohort study in Ontario, CanadaNARA Subscribed
Background Colorectal cancer (CRC) is the second most common cause of cancer death in Canada. Immigrants in Ontario, Canada’s most populous province, are known to have lower rates of CRC screening, but differences in stage of CRC diagnosis are not known. Methods We utilized linked administrative databases to compare early (stage I–II) versus late (stage III–IV) stage of CRC diagnosis for immigrants versus long-term residents a...