Sporothrix brasiliensis is the predominant etiological agent of feline sporotrichosis in Brazil, where zoonotic dissemination represents an escalating public health concern. Reports of therapeutic refractoriness and the emergence of itraconazole-resistant isolates underscore the pressing need for alternative antifungal strategies. This study evaluated in vitro antifungal activity of a biogenic silver nanoparticle against 24 Br...

Since the 1990s, Acinetobacter baumannii has become a major global concern owing to its high incidence in hospital-acquired infections. Although antimicrobial resistance is a natural process, it has been enhanced by the widespread use of antimicrobials in human and animal healthcare and is considered a global priority in the development of new drugs. Therefore, antibacterial photodynamic therapy has gained prominence for treat...

Maternal chromium (Cr) supplementation has been associated with altered offspring growth, carcass traits, and tissue gene expression in several species, but underlying programming mechanisms in sheep remain unclear. This study evaluated the effects of late-gestation and early-lactation dietary chromium propionate in ewes on the expression of genes related to myogenesis and lipid metabolism in the progeny. Sixty-nine Dorper × S...

Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...

Rationale Caffeine had been proposed as an adjuvant therapy for Attention Deficit and Hyperactivity Disorder (ADHD). Although caffeine can ameliorate some ADHD-related behaviors, its effects on impulsivity (more prevalent in boys) and potential sex differences, remains unclear. Objectives To assess sex differences in responsiveness to chronic caffeine on impulsive choice, brain cell composition and serotonergic markers in an A...