Background Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America, primarily affecting humans. Reports in non-human primates are rare and provide valuable insight into the environmental circulation of Paracoccidioides spp. and the interface between animal and human infection. Case report We describe a case of disseminated PCM in a 13-year-old black lion tamarin ( Leontopithecus chrysopygus ) from São Paulo...

Background Chronic inflammatory pain is associated with persistent sensory and immune dysregulation. We evaluated the therapeutic efficacy of two cannabinoids formulations—Cannabigerol (CBG) and Standardized Full-Spectrum Cannabis Extract (FULL) in a preclinical model of acute and Chronic inflammatory pain and examined their effects on peripheral and central inflammatory mediators. Methods Cannabinoid analgesic effects were as...

Tropical wetlands have historically been resilient to fire, but ongoing climate and hydrological changes are undermining this stability. Here, we provide robust multi‐decadal evidence (1985–2024) of structural changes in the contemporary fire regime of the Pantanal, the world's largest wetland, associated with hydroclimatic disruption. We investigated changes in burned area, mean fire size, and fire seasonality using hydrologi...

Since the 1990s, Acinetobacter baumannii has become a major global concern owing to its high incidence in hospital-acquired infections. Although antimicrobial resistance is a natural process, it has been enhanced by the widespread use of antimicrobials in human and animal healthcare and is considered a global priority in the development of new drugs. Therefore, antibacterial photodynamic therapy has gained prominence for treat...

Expanding integrative cytogenetic and molecular analyses is essential for understanding the evolutionary dynamics of chromosome number variation in fishes. This study presents the first cytogenetic characterization of Hypostomus sertanejo , an endemic species native to the semi-arid Jaguaribe River basin in Northeastern Brazil. Cytogenetic analysis revealed a diploid number of 2n = 52, which is the lowest documented for the ge...

Acute pancreatitis is an inflammatory condition characterized by an intense systemic inflammatory response and increased oxidative stress, which may compromise distant organs such as the lungs. In this context, natural compounds with antioxidant and anti-inflammatory properties have been investigated as potential therapeutic agents. Therefore, this study aimed to evaluate the effect of the fixed oil from Syagrus coronata in an...

The sustainable supply of n-3 long-chain polyunsaturated fatty acids ( n -3 LC-PUFA) remains a major challenge for global aquaculture. Although plant oils, microalgae, genetically modified crops, insects, krill, and fish by-products have been explored as alternative sources, none currently provides a stand-alone solution for meeting the growing demand of n -3 LC-PUFA in aquafeeds’ production. Here, we present marine gammarids...

North American Vitis species serve as a vital reservoir of genetic variation, offering valuable resources for molecular breeding programs focused on developing cultivars with enhanced resistance, adaptability, and quality traits for sustainable viticulture. The effective conservation and utilization of collections involving these species require a thorough understanding of their genetic diversity, population structure, and gen...