Anthropogenic habitat transformation has led to population declines and increasing isolation of populations of many species, particularly top predators, where small and fragmented populations often experience limited dispersal and reduced genetic diversity. Jaguars ( Panthera onca ), for example, have lost half of their historical range and most populations outside the Amazon biome are small, isolated and highly threatened. He...

The current generation of sequencing technologies can produce terabases of data with exceptional accuracy and speed, at a fraction of the cost of older methods. Despite this unprecedented power, adoption into aquaculture health management presents several challenges, including identifying where such capability may be optimally deployed. Here we synthesise discussions from a structured expert workshop held at the 2025 Aotearoa...

Primates can share parasites with humans, and understanding host-parasite interactions is essential for evaluating the condition of wild primates, ecological dynamics, and One Health interface, which integrates humans, animal, and environmental health in shared environments. One example is filarial nematodes of the genus Mansonella , for which a lack of in-depth studies of symptoms or blood alterations limits our understanding...

This study evaluates epidote chemistry as a discriminator of and vector to skarn mineralization, based on LA-ICP-MS analyses of epidote from the Devonian Dolphin Tungsten (W) skarn and Neoproterozoic mafic volcanic rocks (up to 6.5 km northeast from the deposit) on King Island, Tasmania. Epidote from the mafic volcanics has distinctive compositions relative to skarn epidote and metamorphic signatures and records a distal footp...

Accurate and precise wood volume estimates are vital for sustainable forest management and are typically obtained using sample-based estimators. This study explores cluster sampling for estimating wood volume in an Amazonian forest, aiming to: (1) measure the loss of precision and deviation in volume estimates by comparing full samples to reduced samples and (2) analyze how the distance between cluster subunits affects the vol...

The novelty of this study lies in the integration of fermentation in a magnetically stabilized fluidized bed bioreactor with S. cerevisiae supported on calcium alginate with magnetic particles and using levoglucosan, a pyrolytic sugar from sugarcane bagasse, as a substrate for bioethanol production. Sugarcane bagasse was pretreated with acetic acid to remove alkali/alkaline earth metals (AAEMs) aiming to intensify levoglucosan...

Life’s Essential 8 (LE8) provides a multidimensional framework to assess cardiovascular health (CVH) in aging populations. The objective of this study was to describe LE8 component scores and their variation by age, sex, and psychosocial factors in middle-aged and older adults from Cádiz, Spain. Cross-sectional data were analyzed from 495 adults aged 50–79 years (59.4% women; 34.7% ≥ 65 years). LE8 scores were calculated follo...

Receptor Activity-Modifying Protein 1 (RAMP1) is a Calcitonin Receptor-Like Receptor (CALCRL)-associated protein with significant relevance in oncogenesis and tumor progression. It acts as a context-dependent allosteric modulator of GPCRs. This integrative review synthesizes evidence from multiple omics layers—transcriptomics, proteomics, epigenomics, and pan-cancer datasets—to clarify the role of RAMP1, its signaling pathways...

Chronological age is a common and non-modifiable factor for chronic disease, but does not fully explain age-related changes. Biological clocks have been developed to explore biological aging mechanisms. They could help identify protective factors against accelerated aging and associated diseases. We aim to assess the association between reduced epigenetic or inflammatory aging and ideal cardiovascular health or cardiovascular...