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Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversityNARA Subscribed
Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...
Learn to listen and listen to learn: reflections from a co-production process between researchers and composersNARA Subscribed
As platforms for dialogue, art-science collaborations hold the potential to cross disciplinary boundaries to better understand and engage the public in addressing sustainability challenges. Moving beyond documenting outcomes, this study details how researchers and composers combined science communication and artistic expression to co-produce performances as part of the Baltic Sea Festival Science Lab. Drawing on insights from...
Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshopNARA Subscribed
Artificial Intelligence (AI) is increasingly influencing chemical risk assessment, enabling faster, more comprehensive, and potentially more ethical assessments. The application of AI in chemical risk assessment refers to both generative and predictive algorithms encompassing machine learning, to analyse complex chemical, biological, and environmental data and provide insights into adverse effect potential for humans and ecosy...
Animals maintain close associations with diverse microbiota that inhabit their digestive tracts, and these associations can profoundly affect host physiology and fitness. Gut microbiome composition is shaped by both host traits and environmental factors, yet the relative importance of these forces remains unclear in many taxa, including squamate reptiles (lizards and snakes). To address this gap, we analysed the gut microbiome...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Full Manure Recycling Risks an 18% Rise in China's Cropland N 2 O Emissions Without Improved ManagementNARA Subscribed
Cropland fertilization is the largest anthropogenic source of nitrous oxide (N 2 O‐N) emissions in China and could be mitigated through manure substitution. However, accurate quantification of N 2 O‐N losses under different combinations of manure and chemical fertilizer applications remains challenging due to limited national data, oversimplified methods of estimation, and neglect of the nitrogen (N) source (chemical‐N and man...
Increased Soil Carbon and Nitrogen Stocks Associate With Stronger Calcium–Microbial and Multi‐Trophic Interactions Under WarmingNARA Subscribed
Converting cropland to planted forests improves soil organic carbon (SOC) and total nitrogen (TN) storage while contributing to climate change mitigation, primarily through the regulation of belowground organisms and mineral protection such as calcium (Ca). However, the mechanistic pathways linking exchangeable Ca 2+ , soil micro‐food web interactions, and nutrient accumulation under warming remain unclear. Here, we investigat...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...