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Recent fissure-fed eruptions from the Svartsengi Volcanic System have significantly impacted Iceland’s Reykjanes Peninsula. With eruptions likely to continue intermittently for decades to centuries, exploring the controls on the locations of fissure-fed eruptions is important for hazard assessment and risk mitigation. This study maps eruptive fissures from six eruptions from December 2023 to September 2024 using satellite and...
Advancing provitamin A biofortification in sorghum: from allele mining and marker development to prebreeding and breedingNARA Subscribed
Key message Allele mining for provitamin A biofortification in sorghum is advanced with new pre-bred germplasm and markers that are trait-predictive in diverse germplasm and breeding programs. Abstract Provitamin A biofortification of the staple cereal crop sorghum ( Sorghum bicolor [L.] Moench) could reduce vitamin A deficiency in low-income countries of sub-Saharan Africa. To advance mining of alleles that confer high provit...
Neonicotinoids (NEOs) are the most widely used class of insecticides worldwide. Consequently, human exposure occurs through multiple pathways, including dietary intake and environmental contact. Previous analytical methods have primarily focused on parent compounds, often excluding key metabolites due to matrix effects and poor quantification in complex biological samples. This gap severely limits the ability to accurately ass...
Swift SNPs: Evaluating Rapid DNA Extraction Methods for Scalable Genotyping in AquacultureNARA Subscribed
Efficient DNA extraction is critical for high-throughput genotyping in aquaculture breeding programs, where cost, speed, and data quality must be balanced. This study compared five rapid extraction methods—HotSHOT, Chelex, Tween, wax-coated dipstick, and bare dipstick—against a conventional cetyltrimethylammonium bromide (CTAB) protocol for use in Lates calcarifer (barramundi) genotyping. DNA yield, purity, and integrity were...
A Randomised Controlled Trial of SFX-01 After Subarachnoid Haemorrhage — The SAS StudyNARA Subscribed
SFX-01 is a novel drug for clinical delivery of sulforaphane (SFN). SFN is a potent nuclear factor erythroid 2-related factor 2 activator that reduces inflammation and oxidation, improving outcomes after subarachnoid haemorrhage (SAH) in animal models. This was a multi-centre, double-blind, placebo-controlled, parallel-group randomised clinical trial to evaluate the safety, pharmacokinetics and efficacy of 28 days of SFX-01 30...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Examining the Role of Marine Mammals and Seabirds in Southeast Alaska’s Marine Ecosystem DynamicsOA Marine
Primary producers are the foundation of marine food webs and require reliable nutrient sources to maintain their important role with ecosystems. While marine mammals and seabirds can play critical roles in marine nutrient cycling, their contributions are often overlooked. Southeast Alaska’s marine environment supports abundant marine mammal and seabird populations in addition to valuable fisheries. Nonetheless, there is still...
Functional traits driving species role in the structure of terrestrial vertebrate scavenger networksNARA Subscribed
Species assemblages often have a non‐random nested organization, which in vertebrate scavenger (carrion‐consuming) assemblages is thought to be driven by facilitation in competitive environments. However, not all scavenger species play the same role in maintaining assemblage structure, as some species are obligate scavengers (i.e., vultures) and others are facultative, scavenging opportunistically. We used a database with 177...
The effects of climate change during the Terminal Pleistocene–Early Holocene transition on ecosystems and early Prearchaic hunter‐gatherers in the central Great Basin of North America are not well understood. We present a palynological reconstruction of regional vegetation and fire history in Grass Valley, central Nevada, from ~14 to ~7.5k cal a BP showing that Pinus ‐dominated woodlands were replaced by dry‐adapted steppe and...
Scavenging in the Anthropocene: Human impact drives vertebrate scavenger species richness at a global scaleNARA Subscribed
Understanding the distribution of biodiversity across the Earth is one of the most challenging questions in biology. Much research has been directed at explaining the species latitudinal pattern showing that communities are richer in tropical areas; however, despite decades of research, a general consensus has not yet emerged. In addition, global biodiversity patterns are being rapidly altered by human activities. Here, we aim...
Summary The rulAB operon of P seudomonas spp. confers fitness traits on the host and has been suggested to be a hotspot for insertion of mobile elements that carry avirulence genes. Here, for the first time, we show that rulB on plasmid pWW 0 is a hotspot for the active site‐specific integration of related integron‐like elements ( ILE s) found in six environmental pseudomonads (strains FH 1– FH 6). Integration into rulB on pWW...