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Glaucoma is a complex neurodegenerative disease with multiple subtypes, yet all are characterized by the progressive dysfunction and loss of retinal ganglion cells (RGCs), which ultimately results in vision impairment and blindness. Elevated intraocular pressure (IOP) is a major risk factor for glaucoma; however, it is neither necessary nor sufficient for glaucomatous neurodegeneration, as patients can exhibit high IOP without...
Addressing urgent conservation issues, such as the drastic declines of North American migratory birds, requires creative, evidence‐based, efficient, and collaborative approaches. The abundance of over 50% of monitored North American shorebird populations has declined by over 50% since 1980. To address these declines, we developed a partnership of scientists and practitioners called the Shorebird Science and Conservation Collec...
Water Exchange Characteristics of Tidally Influenced Hydrilla Invasion Sites in the Lower Connecticut RiverNARA Subscribed
The Lower Connecticut River (CR) is an ecologically and recreationally significant ecosystem within New England, but the river has become increasingly vulnerable to the intrusion of aquatic invasive species (AIS) like hydrilla ( Hydrilla verticillata ). The hydrilla population recently discovered in the Lower CR is genetically unlike former hydrilla clades present in the United States. The specific biological and management co...
Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse miceNARA Subscribed
Adult hippocampal neurogenesis—the generation of new neurons in the adult brain—declines with age, contributing to cognitive deficits in aging. While the majority of mammalian studies on neurogenesis have utilized inbred mouse strains, these models do not fully capture the genetic diversity of humans, limiting the translational relevance of their findings. The Diversity Outbred (DO) mouse model, a genetically heterogeneous pop...
Piñon–juniper (PJ) woodlands are a dominant community type across the Intermountain West, comprising over a million acres and experiencing critical effects from increasing wildfire. Large PJ mortality and regeneration failure after catastrophic wildfire have elevated concerns about the long‐term viability of PJ woodlands. Thinning is increasingly used to safeguard forests from fire and in an attempt to increase climate resilie...
Degradation of the natural world and associated ecosystem services is attributed to a historical failure to include its ‘value’ in decision-making. Uncertainty in the quantification of the relationship between natural capital ‘assets’ that give rise to critical societal benefits and people is one reason for the omission of these values from natural resource management. As this uncertainty increases in marine systems and furthe...