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Electronic cigarette (e-cigarette) use continues to rise, yet the toxicological mechanisms by which inhaled aerosols impair airway epithelial integrity remain poorly defined. E-cadherin, a key adherens junction protein required for epithelial cohesion, can undergo proteolytic cleavage to generate soluble E-cadherin (sE-cad), a mediator of epithelial barrier dysfunction and inflammation. We hypothesized that e-cigarette aerosol...
Paleoenvironments of the Late Quaternary Tonica thermokarst lake, northeastern Illinois, USA, and an extinct elk‐moose ( Cervalces )NARA Subscribed
The Tonica Depression (TD), a late Quaternary sediment‐filled basin in northeastern Illinois, formed as a thermokarst lake as evidenced by a basal trash layer, its depositional history, and its occurrence on a late‐Pleistocene permafrost landscape. Stratigraphy and radiocarbon ages reveal that a multiproxy paleoenvironmental record extends throughout the late Wisconsin. Burning of organically enriched sediments has abbreviated...
Addressing urgent conservation issues, such as the drastic declines of North American migratory birds, requires creative, evidence‐based, efficient, and collaborative approaches. The abundance of over 50% of monitored North American shorebird populations has declined by over 50% since 1980. To address these declines, we developed a partnership of scientists and practitioners called the Shorebird Science and Conservation Collec...
Who needs closure? Estimating abundance with a Markovian availability model for geographically open removal samplingNARA Subscribed
Removal sampling is an important method for estimating abundance, but nearly all removal models assume closure during sampling. Yet, closure may be difficult to assume, evaluate, or enforce in many settings. To address situations where populations are geographically open between each removal sample, we incorporated a Markovian availability process into an N‐mixture model framework. This model relates local abundance available...
Objective This study investigated how cumulative environmental exposures influence offspring behaviour and inflammation-related molecular signatures in the brain and peripheral immune system. Methods A novel "triple-hit" mouse model was developed using C57Bl/6JAusB mice (N = 70), combining preconceptual social stress, antenatal high-fat diet, and a postnatal immune challenge (poly(I:C), 10 mg/kg). At 12 weeks, offspring underw...