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NARA Subscribed1
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Springer Nature1
Journal
Psychopharmacology1
Publication Year
20261
Evan Knep results 1 · Newest (Page 1/1, per page 25)
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16p11.2 duplication and NMDA receptor antagonism have distinct impacts on reward learning and decision makingNARA Subscribed
Psychopharmacology · 2026 · Springer
Dana Mueller; Evan Knep; Angelica Velosa; Erin Giglio; Cathy S. Chen; Sarah R. Heilbronner; R. Becket Ebitz; Patrick E. Rothwell; Nicola M. Grissom
Rationale 16p11.2 duplication is associated with numerous neuropsychiatric conditions at a genome-wide level, including psychosis. Mice modeling 16p11.2 duplication may provide important insights into cognitive risk factors, in particular in reward-guided decision making. NMDAR function has also been implicated in psychosis phenotypes, but whether these phenotypes differ by genetic risk factor is unknown. Objectives We aimed t...
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