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Controlled co-delivery of anti-inflammatory drugs from bilayer polymer films coating a meniscus implantNARA Subscribed
Knee osteoarthritis (OA), a degenerative joint disease, is increasingly prevalent worldwide and often results from a meniscal deterioration that leads to meniscus removal. Replacing the damaged meniscus with a non-biodegradable prosthesis offers an innovative solution to prevent OA progression, particularly in older patients. However, the long-term use of anti-inflammatory drugs for pain relief and prosthesis integration can c...
The expansion of aquaculture and the rising cost of fishmeal have driven research into fish gut health and the replacement of marine-derived ingredients with alternative protein sources, within sustainable strategies aligned with the Blue Transformation. In this sense, the objective of this study was to evaluate the effect of including a functional ingredient based on hydrolyzed microalgae and grape marc extracts in feeds with...
Oxidative stress contributes to age-related musculoskeletal decline, partly through disruption of glutathione-dependent redox homeostasis. Although creatine and β-hydroxy-β-methylbutyrate (HMB) have been individually linked to antioxidant and cytoprotective effects, their combined influence on systemic redox balance in older adults remains insufficiently characterized.To examine the effects of creatine plus HMB supplementation...
Combining Population Genomics With Ancient DNA to Understand Island Colonisation History of the Madagascar Turtle DoveNARA Subscribed
The Mascarene archipelago (Mauritius, Reunion and Rodrigues), characterised by first human arrival being recent, offers a unique setting to study species colonisation on a recent timescale, and contribution of past human interventions. Here we use a combination of modern and ancient DNA data as a case study to investigate the colonisation history of a species of concern in relation to conservation programmes—the Madagascar tur...
Under the current global biodiversity crisis, there is a need for automated and noninvasive monitoring techniques that can gather large amounts of data cost‐effectively at various ecological scales, from local to large spatial scales. These data can then be analyzed to inform stakeholders and decision‐makers. One such technique is passive acoustic monitoring, which is commonly coupled with automatic identification of animal sp...
Patterns of circulating cytokines after 2 types of exercise in active type-1 diabetic patientsNARA Subscribed
Aerobic training (beneficial for type 1 diabetes mellitus (T1DM) patients) could result boring, leading to inactivity or suboptimal performance. Therefore, High-Intensity Interval Training (HIIT) could be an appealing alternative. The present study aimed to compare modulation of certain inflammatory cytokines in T1DM participants performing aerobic vs. HIIT routines. We recruited 26 T1DM male subjects: ages 18–40, T1DM ≥ 2 yea...
Late Quaternary population expansion in gray brocket deer [ Subulo gouazoubira (G. Fisher, 1814), Cervidae, Mammalia] in BrazilNARA Subscribed
There is little information about the changes in the abundance of mammalian species in South America during the late Quaternary, which is a key parameter to understanding past ecological and evolutionary dynamics. Here, we describe a conspicuous increase in the abundance of the gray brocket deer ( Subulo gouazoubira G. Fisher, 1814; Mammalia) during the late Quaternary in Brazil based on paleontological evidence. We studied th...
The environmental variability of rivers and tides create complex mixing patterns, which modulate the estuarine ecosystem services. Therefore, a thorough understanding of these systems is vital, not only for their protection but also for their recovery. This study first applies a method to analyze the different mechanisms driving the mixing and stratification of the water column in Suances estuary, a small estuary with large in...
A Natural Disaster Exacerbates and Redistributes Disease Risk Among Free‐Ranging Macaques by Altering Social StructureNARA Subscribed
Climate change is intensifying extreme weather events, with severe implications for ecosystem dynamics. A key behavioural mechanism whereby animals may cope with such events is by altering their social structure, which in turn could influence epidemic risk. However, how and to what extent natural disasters affect disease risk via changes in sociality remains unexplored in animal populations. By simulating disease spread in fre...