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In Vivo Clearance of Immune Complexes: Insights Into Human Drug/Anti-Drug Antibody Complex Clearance DynamicsNARA Subscribed
Immunogenicity of monoclonal antibodies (mAbs) and other biotherapeutics remains a significant clinical challenge. The resulting anti-drug antibodies (ADAs) can neutralize the drug, accelerate its clearance, diminish efficacy, and potentially trigger hypersensitivity reactions via the formation of immune complexes (ICs). Current pharmacokinetic (PK) and ADA assays typically measure the drug or ADAs but provide limited informat...
Billfish rostra potentially have several functions; however, their role in feeding is unequivocal in some species. Recent work linked morphological variation in rostral micro‐teeth to differences in feeding behavior in two billfish species, the striped marlin ( Kajikia audax ) and the sailfish ( Istiophorus platypterus ). Here, we present the rostral micro‐tooth morphology for a third billfish species, the blue marlin ( Makair...
Lacunae rostralis: A new structure on the rostrum of sailfish Istiophorus platypterusNARA Subscribed
Recent comparative studies of billfishes (Istiophoridae and Xiphiidae) have provided evidence of differences in the form and function of the rostra (bill) among species. Here, we report the discovery of a new structure, lacuna rostralis, on the rostra of sailfish Istiophorus platypterus , which is absent on the rostra of swordfish Xiphias gladius , striped marlin Kajikia audax and blue marlin Makaira nigricans . The lacunae ro...
A new gravity survey (1164 gravity stations and 180 samples for density analysis) combined with two new geological cross sections has been carried out in a sector of the Central Pyrenees in order to improve the characterization of basement and cover architecture. From North to South, the study area comprises the southern half of the Axial Zone and the northernmost part of the South-Pyrenean Zone. New gravity data were combined...
Identifying biological affinities of Holocene northern Iberian populations through the inner structures of the upper first molarsNARA Subscribed
Neolithisation was a relatively fast process that affected both the interior and coastal zones of the Iberian Peninsula, but it was also a heterogeneous process that had diverse impacts on genomic and cultural diversity. In the Late Neolithic–Chalcolithic, a change in funerary practices, cultural material and trade networks occurred, and genomic heterogeneity decreased, suggesting human mobility and genetic admixture between d...
Vertical zonation and functional diversity of fish assemblages revealed by ROV videos at oil platforms in The GulfNARA Subscribed
An assessment of vertical distribution, diel migration, taxonomic and functional diversity of fishes was carried out at offshore platforms in The (Arabian–Iranian–Persian) Gulf. Video footage was recorded at the Al Shaheen oil field between 2007 and 2014 using a remotely operated vehicle (ROV). A total of 12 822 individual fishes, from 83 taxonomic groups were recorded around the platforms. All the species identified are consi...
Although dispersal distance plays a major role in determining whether organisms will reach new habitats, empirical data on the environmental factors that affect dispersal distance are lacking. Population density and kin competition are two factors theorised to increase dispersal distance. Using the two‐spotted spider mite as a model species, we altered these two environmental conditions and measured the mean dispersal distance...
Poster abstractsNARA Subscribed
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