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Authigenic grey monazite from Ordovician metasediments of the Iberian massif: the Matamulas placerNARA Subscribed
Authigenic nodular monazite occurs in dark, Middle Ordovician, low-grade metapelites of the Central Iberian and West Asturian-Leonese Zones of the Iberian Massif. Erosion of monazite-bearing slates and phyllites, and short-range transport resulted in localised recent alluvial deposits rich in millimetre-size monazite, of which the Matamulas site, within the Central Iberian Zone, represents one of the most extensive and potenti...
Key factors of the deranged antiviral response in elderly patients with COVID-19: a machine-learning analysisNARA Subscribed
Age is a well-known risk factor to develop severe viral respiratory infections, including severe COVID-19. This study aimed to identify the biological alterations linked to severe disease in elderly patients with COVID-19. For this purpose, we employed a derivation cohort with 450 SARS-CoV-2 infected and unvaccinated patients admitted to hospital wards and a validation cohort with 244 SARS-CoV-2 infected and unvaccinated patie...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
A case for monitoring fungi of clinical relevance at beaches: enterococci measures do not correlate with all disease risksNARA Subscribed
Fungal disease is on the rise, coupled with fungal pathogens increasing in geographic range. Studies have shown that viable fungal pathogens may be present in beach sand and water, and consequently, efforts are ongoing in Europe to develop guidelines for fungi levels at beaches. In the USA, fungal diseases are a growing concern, and yet, they are not subject to public health reporting, and beach environments are currently not...
This study introduces the first high-resolution hazard probability maps of extreme precipitation for Spain, marking a significant step toward a national climate service for hydrometeorological extremes. Using long-term daily precipitation records from a dense network of stations and incorporating topographic data, the methodology combines the Generalized Pareto distribution with universal kriging to spatially interpolate distr...
Exploring In Vitro Mesenchymal Stem Cell Osteodifferentiation via Vibrational Microspectroscopy: A ReviewNARA Subscribed
The application of vibrational microspectroscopy to the study of in vitro mesenchymal stem cells (MSC) osteogenic differentiation is a promising approach towards the understanding of the molecular processes involved in bone fabrication. Both infrared (IR) and Raman microspectroscopies have been applied, with a clear predominance of the latter. Bone marrow MSC have been the target of most studies, followed by those originating...