The most prevalent form of primary liver cancer and one of the chief drivers of cancer-related mortality globally is hepatocellular carcinoma (HCC). Imminent evidence has indicated that non-coding RNAs (ncRNAs) play an integral part in the development and propagation of HCC. RNA stabilization, transcription regulation, chromatin and genomic architecture remodeling, enhancer-associated activity, and other varied properties set...

Recirculating Aquaculture Systems (RAS) have emerged as a sustainable approach to intensive fish production. In our previous work, we demonstrated the efficacy of a Deep Deterministic Policy Gradient (DDPG) reinforcement learning approach for optimizing feeding rates and maintaining water quality in RAS. However, the “black box” nature of deep reinforcement learning algorithms often impedes their adoption by fish farmers who l...

Optimizing feeding rates in recirculating aquaculture systems (RAS) is crucial for ensuring fish growth, health, and system efficiency. This research introduces a novel approach to RAS feeding control using a Deep Deterministic Policy Gradient (DDPG) reinforcement learning algorithm. The developed system integrates feeding rate optimization with comprehensive water quality management to improve overall performance and stabilit...

Pollution resulting from textile industries wastewater, affects aquatic life, groundwater, crops, and human life. Hence, using membrane-based filtration technology to treat produced water opens new avenues for water recovery. In this work, polyvinylidene fluoride (PVDF) membranes with triethanolamine (TEA) and polyethylene glycol (PEG) were synthesized and tested as ultrafiltration (UF) materials for textile wastewater removal...

Empagliflozin (EMPA) is one of the sodium/glucose cotransporter 2 (SGLT2) inhibitors that has been recently approved for the treatment of diabetes mellitus type II. Recently, EMPA has shown protective effects in different neurological disorders, besides its antidiabetic activity. Kindling is a relevant model to study epilepsy and neuroplasticity. This study aimed to investigate the potential protective effects of EMPA (1 and 3...

PIWI-interacting RNAs (piRNAs) have received a lot of attention for their functions in cancer research. This class of short non-coding RNAs (ncRNA) has roles in genomic stability, chromatin remodeling, messenger RNA (mRNA) integrity, and genome structure. We summarized the mechanisms underlying the biogenesis and regulatory molecular functions of piRNAs. Among all piRNAs studied in cancer, this review offers a comprehensive an...

Semaglutide (SEMG) is one of the most widely used and trending medications to treat type II diabetes and obesity. This work aimed to develop a liquid chromatography with spectroflourimetric detection (HPLC-flourimetry) analysis of SEMG in both its tablet dosage form and plasma. The power of fluorescence detection coupled with HPLC proved its capability as a bioanalytical tool to assay SEMG in plasma samples owing to its simpli...

A new fractional non-Fourier (Cattaneo) photovoltaic (PV) model is presented to enhance the thermal performance of a PV system combined with a heat spreader (HS). The fractional Cattaneo model is shown to be effective in examining transient processes across the entirety of a PV system, in contrast to the conventional Fourier model’s inability to predict system performance. Consequently, a comparison is conducted between the cl...

Hydrogen energy, as clean and efficient energy, is considered significant support for the construction of a sustainable society in the face of global climate change and the looming energy revolution. Hydrogen is one of the most important chemical substances on earth and can be obtained through various techniques using renewable and nonrenewable energy sources. However, the necessity for a gradual transition to renewable energy...

Haloalkophilic bacteria have a potential advantage as a bioremediation organism of high oil-polluted and industrial wastewater. In the current study, Haloalkaliphilic isolates were obtained from Hamralake, Wadi EL-Natrun, Egypt. The phenotype script, biochemical characters, and sequence analysis of bacterial-16S rRNA were used to identify the bacterial isolates; Halomonas HA1 and Marinobacter HA2 . These strains required high...

Kareem Formation is one of the most important hydrocarbon reservoirs in the Gulf of Suez. It contributes significantly to the total Egyptian oil production; therefore, the current work is to emphasise the influence of siliclastic facies types and their diagenetic processes on the reservoir quality of the Kareem Formation. A comprehensive log and core analyses were used to determine both the petrophysical and petrographical cha...

The future of aquaculture development is directed toward high intensification to overcome the decline in natural fishing and to provide enough protein for the increasing world population. The spread of aquaculture production and intensification requires the search for high-quality, new efficient feed ingredients with low cost and sustainable importance. Therefore, the current study aimed to detect the effects of partial or tot...

Purpose To investigate men’s experiences of receiving external-beam radiotherapy (EBRT) with neoadjuvant Androgen Deprivation Therapy (ADT) for localized prostate cancer (LPCa) in the ProtecT trial. Methods A longitudinal qualitative interview study was embedded in the ProtecT RCT. Sixteen men with clinically LPCa who underwent EBRT in ProtecT were purposively sampled to include a range of socio-demographic and clinical charac...