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Water, soil, and nutrient losses related to surface runoff in conventional and conservationist horticultural systemsNARA Subscribed
Purpose This study aimed to quantify the losses of water, soil, and nutrients through surface runoff during natural rainfall events and to evaluate different soil management systems for garlic cultivation. Methods The experiment was conducted using a clayey Cambisol in 2023 and 2024. The crop sequence included cover crops before garlic during autumn/winter, followed by common beans in summer. The treatments included were as fo...
Embryo-fetal and early-life protein restriction programs pulmonary structure and molecular parameters in both dams and female offspringNARA Subscribed
The Developmental Origins of Health and Disease (DOHaD) theory proposes that adverse conditions during critical developmental windows can increase disease susceptibility throughout life. Maternal protein restriction (MPR) is a well-established experimental model that impairs offspring lung development, affecting pulmonary structure, metabolism, and molecular pathways from early life to aging. However, little is known about its...
Association between restless legs syndrome and erectile dysfunction: a systematic review and meta-analysisNARA Subscribed
Objective To evaluate whether patients with RLS have increased odds of ED compared with non-RLS controls. Methods We conducted a systematic review and meta-analysis analyzing the odds of ED in patients with RLS. We included studies that: (i) evaluated adults with a diagnosis of RLS established by the pre-established criteria; (ii) included a control group without RLS; and (iii) evaluated outcomes related to the odds of ED in p...
Multiform glioblastoma (GBM) is the most aggressive primary brain tumor, associated with high heterogeneity, treatment resistance, and poor survival. Temozolomide (TMZ), although the main chemotherapeutic agent used, shows limited efficacy due to low solubility, chemical instability, and acquired resistance. In this context, nanostructured systems can enhance their antitumor efficacy. This study aimed to develop and characteri...
Salt Leaching Mitigates Salinity Impacts on Sugarcane: Effects on Yield, Quality, and Economic ViabilityNARA Subscribed
Climate change has intensified water scarcity, increasing the use of saline water for irrigation. This practice may compromise the sustainability of salt-sensitive crops, such as sugarcane, which is essential for bioenergy production. A potential solution is to adopt management practices based on salt leaching. This study evaluated the effects of salinity on sugarcane yield, technological quality, and economic performance, as...
Integration of Multi-Omics Data To Understand the Multifaceted Role of RAMP1 across Different Cancer TypesNARA Subscribed
Receptor Activity-Modifying Protein 1 (RAMP1) is a Calcitonin Receptor-Like Receptor (CALCRL)-associated protein with significant relevance in oncogenesis and tumor progression. It acts as a context-dependent allosteric modulator of GPCRs. This integrative review synthesizes evidence from multiple omics layers—transcriptomics, proteomics, epigenomics, and pan-cancer datasets—to clarify the role of RAMP1, its signaling pathways...
Understanding variation in home range size (HR) provides important insights into the underlying ecological processes driving space use. However, it remains unclear whether the interspecific allometric scaling of mammals' HR can also be consistently observed within species and for both sexes. To address this knowledge gap, we GPS‐tracked 349 resident individuals across Brazil, encompassing 18 mammal species. We estimated indivi...