Contamination by Alicyclobacillus spp. is a challenge in the juice and acidic beverage industry, since it can cause spoilage and, consequently, economic losses. Natural preservatives are interesting strategies as an alternative search for microbial growth control in food, in particular the use of D-limonene (DL) and nisin (Nis). This study aimed to evaluate the antibacterial activity of the DL combination and Nis against five...

Urban stormwater runoff is an important pathway for transporting microplastics (MPs) from urban environments to marine ecosystems. However, studies investigating how socio-spatial characteristics influence MP abundance and composition remain scarce, particularly in South America. This study evaluated the influence of population density and land use on MP abundance and morphology in stormwater runoff in the coastal zone of Fort...

Obesity and endocrine disruptors (EDs) promote endoplasmic reticulum (ER) stress, a mechanism associated with cardiovascular diseases. Among EDs, BPS is widely used in consumer products. Whether BPS promotes cardiac ER stress, either alone or combined with a high-fat diet, remains unclear. Male C57BL/6 mice were assigned to a standard chow diet (SC—15 kJ/g), SC+BPS (SCB), high-fat diet (HF—21 kJ/g), or HF+BPS (HFB), receiving...

Understanding how multiple interacting stressors modulate aquatic community dynamics is fundamental to forecasting ecosystem trajectories under accelerating global change. In subtropical basins, the concurrent influences of thermal regimes, ionic composition, and habitat structure generate nonlinear and often synergistic ecological responses that remain unresolved. In this study, we integrated community-level indicators with m...

Multiform glioblastoma (GBM) is the most aggressive primary brain tumor, associated with high heterogeneity, treatment resistance, and poor survival. Temozolomide (TMZ), although the main chemotherapeutic agent used, shows limited efficacy due to low solubility, chemical instability, and acquired resistance. In this context, nanostructured systems can enhance their antitumor efficacy. This study aimed to develop and characteri...

Temperature is a key environmental driver of hepatic physiology in ectotherms, and three-dimensional (3D) fish liver models may serve as an ethically advantageous platform to investigate warming effects under controlled conditions while reducing the need for experimental animals. Despite their increasing use in toxicology, their application to assess climate-relevant temperature effects on liver function remains limited. This...

Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...