Purpose To describe the epidemiology, diagnosis, microbiological findings, clinical features, and outcomes of infectious spondylodiscitis (IS). Methods Retrospective analysis of 98 IS patients (2010–2023 - Trieste Hospital). Clinical, radiological, and microbiological data analysed, multivariate logistic regression assessed risk factors for poor outcomes. Results The incidence of IS was 3 cases per 100,000 inhabitants per year...