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The Asia region harbors exceptional chondrichthyan (shark, ray, and chimaera) diversity but faces intense fishing pressure. The Important Shark and Ray Areas (ISRA) process provides a collaborative, evidence-based framework to identify critical habitats and inform spatial management. We assessed ISRAs across the Bay of Bengal, Southeast Asia, and the Northwest Pacific to characterize their extent, ecological significance, and...
Distinguishing climate change worry from state climate anxiety across 32 countries: implications for subjective wellbeingNARA Subscribed
The concepts of “climate change worry” and “climate change anxiety” are often used interchangeably in climate research, but they may reflect distinct emotional responses to climate change, which could potentially have different implications for public mental health. This research brief aims to empirically examine the differences between these two constructs by comparing their associations with key indicators of subjective well...
Micro‐Refuges or Ecological Traps: Context‐Dependent Effects of Rock Pools on Intertidal Biodiversity Across LatitudesNARA Subscribed
Aim We investigated how local‐scale environmental heterogeneity influences biodiversity patterns across broad biogeographic gradients, using intertidal microhabitats as a model system within one of the most environmentally stressful ecosystems on Earth. Location Intertidal habitats at 26 locations (two rocky shore sites per location) across six continents, spanning 98° of latitude (38°S to 60°N). Time Period 2019–2022. Major T...
Genetic basis and role of exotic accessions in cultivated cotton fiber quality improvementNARA Subscribed
Key message Exotic Gossypium accessions still harbor QTL‑validated alleles that, combined with CRISPR pyramiding and genomic selection, can break the entrenched fiber length–strength trade‑off. Abstract Cotton’s four independent domestications twice in diploids and twice in allotetraploids offer a natural experiment in fiber improvement. Synthesizing three decades of data, we chart how polyploidy, selection and modern breeding...
Limited genetic diversity for fiber quality and yield traits in the improved gene pool for Upland cotton motivates the exploration of exotic materials. In the present study, we carried out QTL mapping for 2 fiber yield components in five BC 1 F 2 and one F 3 resembling intermated population(s) involving 5 ‘converted’ exotic lines of Upland cotton and an elite cultivar “DES56,” as a common parent in all populations. The results...
Uncovering the magnitude of African pangolin poaching with extensive nanopore DNA genotyping of seized scalesNARA Subscribed
Trade in pangolins is illegal, and yet tons of their scales and products are seized at various ports. These large seizures are challenging to process and comprehensively genotype for upstream provenance tracing and species identification for prosecution. We implemented a scalable DNA barcoding pipeline in which rapid DNA extraction and MinION sequencing were used to genotype a substantial proportion of pangolin scales subsampl...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Non-clinical Pharmacology of YTX-7739: a Clinical Stage Stearoyl-CoA Desaturase Inhibitor Being Developed for Parkinson’s DiseaseNARA Subscribed
Summary Stearoyl-CoA desaturase (SCD) is a potential therapeutic target for Parkinson’s and related neurodegenerative diseases. SCD inhibition ameliorates neuronal toxicity caused by aberrant α-synuclein, a lipid-binding protein implicated in Parkinson’s disease. Its inhibition depletes monounsaturated fatty acids, which may modulate α-synuclein conformations and membrane interactions. Herein, we characterize the pharmacokinet...
Beyond denitrification: The role of microbial diversity in controlling nitrous oxide reduction and soil nitrous oxide emissionsNARA Subscribed
Many biotic and abiotic processes contribute to nitrous oxide (N 2 O) production in the biosphere, but N 2 O consumption in the environment has heretofore been attributed primarily to canonical denitrifying microorganisms. The nosZ genes encoding the N 2 O reductase enzyme, NosZ, responsible for N 2 O reduction to dinitrogen are now known to include two distinct groups: the well‐studied Clade I which denitrifiers typically pos...
Microbiome and environment explain the absence of correlations between consumers and their diet in Bornean microsnailsNARA Subscribed
Classical ecological theory posits that species partition resources such that each species occupies a unique resource niche. In general, the availability of more resources allows more species to co‐occur. Thus, a strong relationship between communities of consumers and their resources is expected. However, correlations may be influenced by other layers in the food web, or by the environment. Here we show, by studying the relat...