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Microbial decontamination and enhanced extraction of value-added compounds from Spirulina platensis using gamma radiationNARA Subscribed
Spirulina platensis has garnered increasing attention as a valuable source of proteins, lipids, and pigments, with applications in the food, feed, and nutraceutical industries. However, large-scale cultivation in open pond systems is liable to microbial contamination, posing risks to product quality and productivity. This study evaluated the effects of gamma (γ) irradiation up to 10 kilogray (kGy) as a dual strategy for microb...
Multiple Sclerosis (MS) is a chronic immune-mediated neurological disorder frequently accompanied by cognitive impairment, which affects up to 60% of patients and is associated with faster disease progression and greater disability. Interleukin-6 (IL-6), a key proinflammatory cytokine involved in neuroinflammation, has been implicated in MS pathogenesis, and the rs1800795 (−174 G>C) single nucleotide polymorphism (SNP) in the...
The clinical use of dexamethasone (DXM) is associated with the development of non-alcoholic fatty liver disease (NAFLD). However, the mechanisms by which DXM-induced NAFLD is still incompletely known. Therefore, the current study aims to test the hypothesis that DXM-induced NAFLD is mediated by dysregulation of key genes involved in lipid metabolism and liraglutide (LG) can ameliorate these effects. The histopathological and b...