In 2013 QoI-resistant strains of the rice blast fungus (MoO) emerged suddenly and spread in Hyogo Prefecture. To estimate factors associated with their spread and subsequent survival, the population structure of MoO strains was monitored from 2013 to 2017 and 2023 using DNA fingerprinting with Pot2 . Most of the QoI-resistant isolates collected in 2013 were classified into haplotype HY1, irrespective of areas of collection in...

Wheat blast is an important disease that affects cross-border food security. The causal pathogen, Pyricularia oryzae (syn. Magnaporthe oryzae ) Triticum pathotype (MoT), forms a phylogenetic group distinct from the other P. oryzae pathotypes pathogenic on various gramineous plants. Here we developed MoT-specific primer sets for qPCR and LAMP detection methods, and their amplification specificity and efficiency were tested in c...

Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (CANVAS) is an autosomal recessive multisystem neurologic disorder caused by biallelic intronic repeats in RFC1 . Although the phenotype of CANVAS has been expanding via diagnostic case accumulation, there are scant pedigree analyses to reveal disease penetrance, intergenerational fluctuations in repeat length, or clinical phenomena (including heterozygous carrie...