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Impact of neoadjuvant cetuximab on liver function and tumor reduction in a murine model of selective portal vein ligationNARA Subscribed
Colorectal cancer mortality is largely driven by metastatic spread, with colorectal liver metastases (CRLM) being the most frequent. Treatment often combines surgery and systemic therapy, including anti-EGFR agents such as cetuximab. This study evaluated the cytoreductive effect of cetuximab on CRLM and its influence on liver function and regeneration in a selective portal vein ligation (PVL) model. Sixty-six male WAG/RijHsd r...
Accurate knowledge of the global distribution of non-indigenous species (NIS) is essential for understanding their invasion dynamics and for implementing timely management measures. This study reports the first records of the marine amphipod Aoroides longimerus, putatively native to the East Asian coast, in Italy (2018), Spain (2019) and Tunisia (2022) and provides the earliest documented record of the species in its introduce...
Predicting the levels of a pollutant in a given area is an open problem, mainly because historical data are typically available at certain locations, where monitoring stations are located, but not at all locations in the area. This work presents an approach based on developing predictions at each of the points where an immission station is available; in this case, based on shallow Artificial Neural Networks, ANNs, and then usi...