Background Circulating tumour cells (CTCs) are key mediators of metastasis and exhibit marked phenotypic plasticity driven by epithelial-to-mesenchymal transition (EMT). Traditional marker-based CTC isolation approaches rely on epithelial marker expression, which may fail to capture mesenchymal and hybrid CTC subpopulations. Hybrid CTCs remain poorly characterised in colorectal cancer (CRC). This study explored transcriptional...

Global trait axes reveal overarching dimensions of plant functional variation. However, how these dimensions are spatially organized within and across forest types remains unclear. We combined drone‐based full‐range imaging spectroscopy with crown‐level measurements of 16 physiological, morphological and biochemical traits across temperate, subtropical and tropical forests in China to enable spatially‐explicit trait mapping. T...

Diapause polymorphisms shape insect life cycles, affecting their responses to seasonal environmental fluctuations. In the spruce bark beetle Ips typographus , diapause phenotypes, classified as facultative or obligate, significantly impact voltinism and thus outbreak potential, yet the genetic mechanisms underlying this trait remain incompletely understood. Here, we combined reduced‐representation genome‐wide association study...