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Circulating succinate changes during acute cold exposure are not related with brown adipose tissue in humansNARA Subscribed
Brown adipose tissue (BAT) activity in humans is linked to better glucose metabolism and cardiometabolic health. In mice, cold exposure increases circulating succinate and enhances BAT thermogenesis, but whether similar succinate responses occur in humans remains undetermined. We analysed data from 33 young (18–25 years), sedentary adults (20 women) from the ACTIBATE cohort (NCT02365129). Plasma succinate was measured enzymati...
Cold exposure activates brown adipose tissue (BAT), a therapeutic target to mitigate cardiometabolic diseases. Emerging evidence suggests that bile acids may influence BAT activity through metabolic and endocrine signaling pathways. Characterizing changes in circulating bile acids during cold exposure may uncover new pathways to improve metabolic health in humans. We analysed 56 young (21.7 ± 2.3 years old), sedentary adults (...
Developmental trajectories are considered plastic phenotypic traits that allow animals to adjust their growth in response to environmental conditions. Plasticity in growth trajectories is likely mediated by parental effects occurring before and after offspring birth, but its relative contribution has rarely been explored in the wild. By swapping first, intermediate, and last hatched nestlings between nests of the European hoop...
The future of how we understand and manage ecosystems largely depends on direct and continuous observations that connect local territories to planetary processes. Latin America (LATAM: Mexico, Central and South America, and the Caribbean) hosts ecosystems critical for regulating global carbon, water, and energy cycles. However, persistent underinvestment in science and technology hampers the long‐term monitoring capacity neede...
Spatial Partitioning of Microbial Functional Potential Suggests Complex Nitrogen Cycling in a Subterranean EstuaryNARA Subscribed
Subterranean estuaries (STEs) are key bioreactors regulating the quantity and chemical composition of groundwater‐derived nitrogen (N) reaching coastal ecosystems. Yet, the microbial controls on N‐cycling within these groundwater–seawater mixing zones remain poorly understood. We investigated the spatio‐temporal variations in microbial communities and their N‐cycling potential within an alluvial Mediterranean STE with high N c...
Photogrammetry has become an essential tool in medical and research fields for generating high-fidelity 3D models from 2D images. However, optimizing the imaging and processing parameters remains a challenge, particularly for fresh brain specimens, where repeated imaging is not feasible. This study systematically evaluates the impact of various Metashape alignment settings on 3D reconstruction outcomes, analyzing 12,600 config...