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Aquaculture is the world’s fastest-growing food production sector, yet it faces major challenges, including limited understanding of the biology of farmed species. In this context, cell lines are becoming increasingly relevant for studying complex traits and their underlying genetic basis. The in vitro application of molecular tools—such as RNA interference and genome editing—can help disentangle the molecular basis of target...
Role of autonomic receptors in ethyl ferulate-induced cardiovascular effects in normotensive and hypertensive female ratsNARA Subscribed
Aims Ethyl ferulate (EF) may offer novel benefits in hypertension. We investigated the contribution of autonomic receptors to EF-induced effects in female Wistar and SHR. Methods Anesthetized females received EF intravenously at 7.5, 15, or 30 mg/kg. Autonomic involvement was evaluated using pretreatment with atropine, atenolol, or hexamethonium. MAP and HR were continuously monitored. Results EF induced rapid and pronounced r...
The Canary Islands region exhibits intense mesoscale activity, with eddies generated south the islands by perturbations of the Canary Current. After detachment, these eddies drift southwestward along the Canary Eddy Corridor (CEC), exporting their properties into the open ocean. While mesoscale dynamics in the region are well documented, associated submesoscale structures and their role in the production, transport and reminer...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Controlled release of chemotherapeutic drugs is a key factor in cancer therapy. In this regard, temperature triggered release of drugs offers a precise control over the release within the tumour region, thus avoiding premature drug release and unspecific toxicity. In this work a novel polymeric N-isopropylacrylamide-based nanocarrier was developed to carry and release doxorubicin in response to the natural higher temperature o...
Major contribution of particle‐associated microbes to deep‐sea organic carbon degradationNARA Subscribed
The biological carbon pump mediates the export of particulate organic carbon from the euphotic zone to the deep ocean, where it provides the base of the food web. Although deep‐sea microbial metabolism is considered to be largely associated with macroscopic particles, such as marine snow, the specific contribution of particle‐associated microorganisms to the utilization of bulk organic matter has rarely been directly quantifie...
A Participatory Decision-making Strategy for Geoconservation Implemented in Portland, JamaicaNARA Subscribed
Geoconservation aims to protect the legacy of the Earth, and an integral component is decision-making. Decisions in geoconservation impact residents and other stakeholders; therefore, strategies to facilitate participatory decision-making are needed. Here, we present a strategy to facilitate the implementation of the Analytic Hierarchy Process (AHP) with a diverse group of stakeholders in Portland, Jamaica, without previous ex...
Ecological resources of a heavily modified and utilised temperate coastal embayment: Cockburn SoundOA Marine
Coastal environments and their associated biota provide numerous environmental, economic and societal services. Cockburn Sound, a temperate embayment on the lower west coast of Western Australia, is immensely important for the State and adjacent capital city of Perth. However, urbanisation and associated terrestrial and marine development has the potential to threaten this important ecosystem. This study collated published and...
Spawning and larval development of the mesophotic octocoral Swiftia exserta in aquariaNARA Subscribed
The 2010 Deepwater Horizon oil spill injured mesophotic and deep-sea environments over a vast area. In order to restore mesophotic and deep-sea coral species impacted by the spill, information on fundamental ecosystem processes such as reproduction is needed. During expeditions in 2021 and 2022, fragments of the mesophotic octocoral Swiftia exserta were collected from the northern Gulf of Mexico and transported to aquaria at f...
Background: Priming strategies that improve the functionality of MSCs may be required to address issues limiting successful clinical translation of MSC therapies. For conditions requiring high trophic support such as brain and spinal cord injuries, priming MSCs to produce higher levels of trophic factors may be instrumental to facilitate translation of current MSC therapies. We developed and tested a novel molecular priming pa...