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Role of autonomic receptors in ethyl ferulate-induced cardiovascular effects in normotensive and hypertensive female ratsNARA Subscribed
Aims Ethyl ferulate (EF) may offer novel benefits in hypertension. We investigated the contribution of autonomic receptors to EF-induced effects in female Wistar and SHR. Methods Anesthetized females received EF intravenously at 7.5, 15, or 30 mg/kg. Autonomic involvement was evaluated using pretreatment with atropine, atenolol, or hexamethonium. MAP and HR were continuously monitored. Results EF induced rapid and pronounced r...
The Canary Islands region exhibits intense mesoscale activity, with eddies generated south the islands by perturbations of the Canary Current. After detachment, these eddies drift southwestward along the Canary Eddy Corridor (CEC), exporting their properties into the open ocean. While mesoscale dynamics in the region are well documented, associated submesoscale structures and their role in the production, transport and reminer...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Spawning and larval development of the mesophotic octocoral Swiftia exserta in aquariaNARA Subscribed
The 2010 Deepwater Horizon oil spill injured mesophotic and deep-sea environments over a vast area. In order to restore mesophotic and deep-sea coral species impacted by the spill, information on fundamental ecosystem processes such as reproduction is needed. During expeditions in 2021 and 2022, fragments of the mesophotic octocoral Swiftia exserta were collected from the northern Gulf of Mexico and transported to aquaria at f...
Introduction Owing to controversy information surrounds effect of glucocorticoids on the evolution of COVID-19, we evaluate the effects of outpatient glucocorticoid use on the severity and progression of COVID-19 and risk of infection and analyse the effect of window of exposure and dose. Methods We conducted a population-based case − control study, involving 4 substudies: (i) Hospitalisation; (ii) Mortality, using subjects ho...
Impact of prior antihypertensive treatment on COVID-19 outcomes, by active ingredientNARA Subscribed
Objectives To assess the impact of prior chronic treatment with angiotensin-converting enzyme inhibitors (ACEIs)/ angiotensin-receptor blockers (ARBs), both as a group and by active ingredient, on severity (risk of hospitalization and mortality), progression of and susceptibility to COVID-19. Methods We conducted a multiple population-based case–control study in Galicia (north-west Spain). The study data were sourced from medi...