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Key factors of the deranged antiviral response in elderly patients with COVID-19: a machine-learning analysisNARA Subscribed
Age is a well-known risk factor to develop severe viral respiratory infections, including severe COVID-19. This study aimed to identify the biological alterations linked to severe disease in elderly patients with COVID-19. For this purpose, we employed a derivation cohort with 450 SARS-CoV-2 infected and unvaccinated patients admitted to hospital wards and a validation cohort with 244 SARS-CoV-2 infected and unvaccinated patie...
Biomechanically Informed Patient-Specific in Silico Models for Laser Refractive SurgeryNARA Subscribed
Purpose: Corneal biomechanics plays a key role in the planning and outcomes of laser refractive surgery. This study presents a validated methodology for simulating patient-specific refractive treatments, focusing on the optomechanical effects of the three most commonly performed procedures: PRK, LASIK, and SMILE. Methods: For the first time, patient-specific mechanical properties of the cornea were incorporated into finite ele...
Consistent topsoil carbon density and driving factors in urban greenspaces and natural ecosystemsNARA Subscribed
Background Urban greenspaces have the potential to mitigate urban carbon footprints by storing soil organic carbon (SOC). Different management and plant communities associated with different types of urban greenspaces may hold contrasting SOC, as well as different proportions of particulate (POC) and mineral-associated organic carbon (MAOC). In addition, management could outweigh the effects of climate or soil properties as dr...
Changes in lithic raw material and technological management during the Mesolithic: a view from El Mazo (Northern Iberia)NARA Subscribed
This study investigates the lithic industry at the Mesolithic shell midden site of El Mazo (Andrín, Asturias), on the Asturian coastline in Northern Iberia, focusing on resource management, production strategies, and mobility patterns of the last hunter-gatherer-fishers. El Mazo provides a unique opportunity to examine lithic resource use across the Early-Middle Holocene transition, with a particular emphasis on the dynamic of...
FRUGIVORY CAMTRAP : A dataset of plant–animal interactions recorded with camera trapsNARA Subscribed
Ecological interactions are a key component of biodiversity, essential for understanding ecosystem services and functioning. Recording and quantifying ecological interactions is challenging, frequently requiring complex logistics and substantial effort in the field. Camera traps are routinely used in ecology for various applications, and have proven to be an excellent method for passive and non‐invasive sampling of plant–anima...
Not only domestic spaces: dismantling short‐term occupations in Level 497D of Cova Gran de Santa Linya (Pre‐Pyrenees, Spain)NARA Subscribed
The Early Upper Paleolithic Level 497D of Cova Gran (Pre‐Pyrenees, Spain) comprises large assemblages of lithics, fauna, hearths, ash accumulations and well‐preserved refitting sequences. This provides exceptional information to analyze spatial patterns and deepen our understanding of the socio‐economic behavior of these human groups. This large interdisciplinary dataset has allowed us to carry out a detailed spatial study bas...
Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 yearsNARA Subscribed
Clonal hematopoiesis, especially that of indeterminate potential (CHIP), has been associated with age-related diseases, such as those contributing to a more severe COVID-19. Four studies have attempted to associate CHIP with COVID-19 severity without conclusive findings. In the present work, we explore the association between CHIP and COVID-19 mortality. Genomic DNA extracted from peripheral blood of COVID-19 patients ( n = 24...
The Fresno-Benavente Pepper (F-BP) Protected Geographical Indication (PGI) is a horticultural crop characterized by its great agronomic, economic and cultural importance in the region of Castilla y León (Spain). Field production is threatened by verticillium wilt caused by Verticillium dahliae and postharvest losses due to grey mould caused by Botrytis cinerea . Eight Bacillus spp. strains endophytically isolated from F-BP roo...