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Rising ocean temperatures and CO 2 concentrations are reshaping phytoplankton physiology, yet how long‐term adaptation to these stressors interacts with nutrient limitation remains poorly understood. Phosphorus (P) frequently limits phytoplankton growth in coastal and stratified oceans, but it remains unclear whether adaptation to warming and elevated CO 2 modifies responses to P limitation and whether such adaptive advantages...
Purpose Randomized evidence for pharmacological interventions in vascular dementia (VaD) is fragmented. We conducted a VaD-focused, scale-specific systematic review and meta-analysis. Methods We searched four databases for English-language parallel-group randomized controlled trials (1990–2025). Comparable placebo-controlled outcomes were pooled using random-effects meta-analysis; non-poolable outcomes were synthesized accordi...
A Musculoskeletal-Finite Element Study of Knee Joint Loading and Cartilage Mechanics in Children with Cerebral PalsyNARA Subscribed
Purpose Cerebral palsy (CP) is typically associated with abnormal gait that may alter knee joint loading and accelerate joint degeneration. We developed an integrated musculoskeletal-finite element (MSK-FE) framework to quantify differences in knee joint biomechanics between children with CP and typically developing (TD) peers. Methods Gait data from 13 children (TD, n = 5; hemiplegia [HP], n = 4; diplegia [DP], n = 4) were an...