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Objective This study aimed to determine the minimum toenail mass needed for reliable fluoride analysis, and to compare fluoride extraction efficiency (%FE) using two protocols. Methods Toenail samples (n = 98 from 11 participants) were grouped into masses ranging from 1.0 to 5.0 mg (± 0.5 mg). Fluoride content was analyzed using a hexamethyldisiloxane(HMDS)-facilitated diffusion method and a fluoride-ion selective electrode. P...
To assess the strength of the relationships between fluoride concentrations in tap water, toenails, and urine in a U.S. cohort of pregnant participants using private, unregulated water systems. We analyzed fluoride concentrations in residential tap water directly with a fluoride-specific electrode, and in toenail and spot urine samples using a micro-diffusion technique. We collected samples from 436 pregnant women in the New H...
Monoclonal antibodies (mAbs) are promising therapeutic agents for neurological disorders due to their high specificity. However, their clinical application is significantly hindered by their poor transport across the blood-brain barrier (BBB) and their limited diffusion within the brain parenchyma. While significant efforts have been oriented to tackle the first barrier, the challenge of efficient brain diffusion remains large...
Under the current global biodiversity crisis, there is a need for automated and noninvasive monitoring techniques that can gather large amounts of data cost‐effectively at various ecological scales, from local to large spatial scales. These data can then be analyzed to inform stakeholders and decision‐makers. One such technique is passive acoustic monitoring, which is commonly coupled with automatic identification of animal sp...
Can Hematological Biomarkers Indicate Diagnoses and Prognosis in Stranded Harbor Seals ( Phoca vitulina )?NARA Subscribed
Wildlife health assessments offer critical insights in applied ecological research, but their interpretation is often limited by missing complementary data. There is heightened need for such data for European harbor seals ( Phoca vitulina vitulina ) given their recent population decline. We investigated trends in and hematological markers of health and survival of pre‐ and post‐ weaned harbor seal pups using a 10‐year rehabili...
Host Co‐Occurrence and Population Size Explain Genetic Differentiation and Diversity in Seal LiceNARA Subscribed
We studied the drivers of population‐genetic structuring and genetic diversity in specialist parasites based on whole‐genome resequencing data from 82 Echinophthirius horridus seal louse individuals sampled from 12 ecologically and behaviourally different phocine seal species, subspecies and populations across the Holarctic. We found that the main genetic disjunctions in E. horridus lice occur across seal host species and subs...
The neurophysiology of healthy and pathological aging: a comprehensive systematic reviewNARA Subscribed
As the population of older adults grows, so does the prevalence of neurocognitive disorders such as mild cognitive impairment (MCI) and dementia. While biochemical, genetic, and neuroimaging biomarkers have accelerated early detection and diagnosis, neurophysiological measures are absent from daily medical use. Electroencephalography (EEG) and magnetoencephalography (MEG) are two non-invasive techniques that measure neurophysi...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
AVOTREX : A Global Dataset of Extinct Birds and Their TraitsNARA Subscribed
Motivation Human activities have been reshaping the natural world for tens of thousands of years, leading to the extinction of hundreds of bird species. Past research has provided evidence of extinction selectivity towards certain groups of species, but trait information is lacking for the majority of clades, especially for prehistoric extinctions identified only through subfossil remains. This incomplete knowledge potentially...
Historical information has provided key insights into long‐term ecological change to marine species and ecosystems, with value to fisheries. Yet, pathways to integrate these diverse data sources into fisheries decision‐making have not been clear. Here, we identify an array of biological, ecological, and social information suitable for contemporary science‐based decision‐making, derived from local ecological knowledge, historic...