L. Watson results 239
· Newest (Page 1/10, per page 25)
Author: L. Watson ×Clear All Filters
Search Results
A primary care pharmacogenetic precision medicine pilot based on specific Māori tribal ethical frameworks and principlesNARA Subscribed
Indigenous tribal communities are frequently underserved by genomic medicine because they are under-represented in research, often live in remote locations and have ethical and cultural perspectives that vary from westernised standpoints. The Rakeiora platform, a permissioning and analytical environment that incorporates Māori perspectives and ethical frameworks on how precision medicine research is best conducted was used to...
Fine‐Scale Ecological Biomonitoring in a Large, Complex Agriculturally Impacted Watershed via eDNA MetabarcodingNARA Subscribed
DNA‐based approaches utilizing high‐throughput sequencing (HTS) (e.g., DNA metabarcoding) have revolutionized ecological biomonitoring by providing higher sample throughput, greater reproducibility, and better cost‐benefits compared to traditional morphology‐based bioassessment studies. Here, we utilized DNA metabarcoding in a watershed in Ontario (Canada) dominated by agricultural land uses. Our aim is to understand patterns...
Epigenomic changes are a hallmark of aging, and DNA methylation (DNAm) has emerged as the most reliable molecular marker of an individual's age. Genome‐wide patterns of age‐associated hypo‐ and hypermethylation have been applied to generate predictive models (i.e., “epigenetic clocks”) capable of estimating chronological age in an increasingly diverse set of species including many mammals, a few birds, a reptile, and several b...
Molecular taxonomy of the guitarfish genus Acroteriobatus (Rhinopristiformes: Rhinobatidae)NARA Subscribed
Guitarfish species (genus Acroteriobatus ) display restricted distributions in undermanaged regions of intense fishing pressure. The importance of accurate specimen identification is well established, especially in the context of conservation management. However, guitarfishes remain poorly understood, which is exacerbated by taxonomic uncertainty due to morphological similarity. We therefore aimed (1) to identify molecular ope...
Size estimation of particles and plankton is key to understanding energy flows in the marine ecosystem. A useful tool to determine particle and plankton size - besides abundance and taxonomy - is in situ imaging, with digital holography being particularly useful for micro-scale ( e.g. , 25 – 2,500 µm) marine particles. However, most standard algorithms fail to accurately size objects in reconstructed holograms owing to the hig...
Soil phosphorus transformations along two long-term chronosequences with contrasting climate in south-western AustraliaNARA Subscribed
Background Soil organic phosphorus (P) and its chemical nature change markedly during long-term pedogenesis, but how variation in ecosystem water balance and associated differences in vegetation impact such transformations remain unclear. Methods We used solution 31 P-nuclear magnetic resonance ( 31 P-NMR) spectroscopy to assess the chemical nature of soil organic P along two > 2-million-year coastal sand dune chronosequences...
Size matters: a new view of the relationship between shape and size for molten volcanic ballisticsNARA Subscribed
Volcanic ballistic projectiles (VBPs) are a common hazard near volcanic vents and often threaten volcano tourists, especially at accessible volcanoes with Strombolian eruption style. Current ballistic hazard models used to estimate potential VBP impact zones often assume round and solid (fixed shape) projectiles, though the validity of these assumptions remains uncertain. In this study, we use high-speed video observations to...
Continental Patterns of Phenotypic Variation Along Replicated Urban Gradients: A Mega‐AnalysisNARA Subscribed
Individual variation among and within natural populations can have eco‐evolutionary implications by, for example, affecting species interactions or evolutionary potential. Urban systems present a unique opportunity to evaluate how environmental change shapes variation since urban phenotypic differentiation is widely documented on contemporary timescales. We introduce and test three hypotheses to determine how urbanisation affe...